| 0 | Our Greatest Issue Ever! | cover | 1 | pencils: Mark Fredrickson; inks: Mark Fredrickson | Alfred E. Neuman |
| 2 | Departments | table of contents | 1 | script: John Ficarra | Alfred E. Neuman; Barack Obama; Sergio Aragones; Groucho Marx; Nadya Suleman |
| 3 | Random Samplings of Reader Mail | letters page | 2.67 | script: John Ficarra, Dalton Vaughn | Alfred E. Neuman; Kiss [Ace Frehley; Gene Simmons; Paul Stanley; Peter Criss]; Steven Ferrara; Neil Cuadra; Joshua Hecht; Dalton Vaughn; Dylan Day; Patrick James Folaron; Noam Chomsky; Ken Hildebrant |
| 6 | - | credits, title page | 0.33 | letters: typeset | |
| 8 | The Fundalini Pages | comic story | 6.5 | script: Jeff Kruse, Duck Edwing, Tom Cheney, Paul Peter Porges, Stan Sinberg, Scott Maiko; pencils: Duck Edwing, Tom Cheney, Sam Sisco, Scott Bricher, Bob Clarke, Paul Peter Porges; inks: Duck Edwing, Tom Cheney, Sam Sisco, Scott Bricher, Bob Clarke, Paul Peter Porges; colors: Carl Peterson; letters: Rob Leigh | Nadya Suleman; Joe Bitterman; Abraham Lincoln; Alex Rodriguez; The Jonas Brothers; Melvin; Jenkins; Barack Obama; Monroe; Monroe's mother; Monroe's father; Rob Blagoevich |
| 9 | Life After Debt | illustration | 1 | pencils: Scott Bricher; inks: Scott Bricher; colors: Scott Bricher | Edward M. Liddy [Notorious A.I.G.] |
| 11 | 500 Issues of Mad: A Visual History | illustration | 10 | script: Sergio Aragonés, Dave Berg, Al Jaffee, Harvey Kurtzman, Don Martin, Nick Meglin; pencils: Sergio Aragonés, Dave Berg, Al Jaffee, Harvey Kurtzman, Don Martin, Bob Clarke; inks: Sergio Aragonés, Dave Berg, Al Jaffee, Harvey Kurtzman, Don Martin, Bob Clarke | |
| 12 | The Dead Celebrity Apprentice | comic story | 6 | script: Desmond Devlin; pencils: Tom Bunk; inks: Tom Bunk | Donald Trump; Ivanka Trump; Cleopatra; Babe Ruth; Adolph Hitler; Groucho Marx; Nero; Jesus Christ; Donald Trump Jr.; Elvis Presley; William Shakespeare; Richard Nixon; Frank Sinatra; Betsy Ross; Andre The Giant |
| 13 | - | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | White Spy; Black Spy; Gray Spy |
| 14 | Planet Tad!!!!! | text story | 2 | script: Tim Carvell | Tad; Cruella DeVille |
| 15 | A Mad Look at Marginals | cartoon | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Tom Luth; letters: Sergio Aragonés | Sergio Aragones; Batman; Spider-Man; Dracula; Black Spy; King Kong; Gulliver |
| 16 | Obey | illustration | 1 | pencils: Jack Syracuse; inks: Jack Syracuse; colors: Jack Syracuse | Rush Limbaugh |
| 17 | The Strip Club | comic story | 5 | script: Jason Yungbluth, Paul Gilligan, Ted Rall, Scott Nickel, Christopher Baldwin, Douglas Paszkiewicz; pencils: Jason Yungbluth, Paul Gilligan, Ted Rall, Scott Nickel, Christopher Baldwin, Douglas Paszkiewicz; inks: Jason Yungbluth, Paul Gilligan, Ted Rall, Scott Nickel, Christopher Baldwin, Douglas Paszkiewicz; letters: Jason Yungbluth, Paul Gilligan, Ted Rall, Scott Nickel, Christopher Baldwin, Douglas Paszkiewicz | Batman; Rex; Fantabulaman; Feralman; starship captain; starship first mate |
| 18 | Great Art Masterpieces and What They Would Be Saying Today | comic story | 2 | script: Adam Rust; pencils: Michelangelo, Myron, Pablo Picasso, Norman Rockwell, Francisco Goya, Edward Hopper; inks: Michelangelo, Myron, Pablo Picasso, Norman Rockwell, Francisco Goya, Edward Hopper; colors: Michelangelo, Myron, Pablo Picasso, Norman Rockwell, Francisco Goya, Edward Hopper | |
| 19 | Mad Googles Google's Headquarters | text story | 1 | script: Ryan Pagelow | |
| 20 | An Important Message from Mad's Director of Business & Development | promo (ad from the publisher) | 1 | script: Jeffrey Lozenge | Jeffrey Lozenge |
| 21 | Insanity Claws | text story | 2 | script: Desmond Devlin | Wolverine; Hugh Jackman |
| 22 | Buy This Stuff Today! | promo (ad from the publisher) | 1 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | Alfred E. Neuman; George Bush; Black Spy; White Spy |
| 23 | The Bailout Hymn of the Republic | comic story | 3 | script: Frank Jacobs; pencils: Mort Drucker, James Warhola, Tom Richmond, Angelo Torres, Hermann Mejía, Gerry Gersten; inks: Mort Drucker, James Warhola, Tom Richmond, Angelo Torres, Hermann Mejía, Gerry Gersten | Barack Obama; Nancy Pelosi; Senator Shelby; Chris Dodd; Barney Frank; Alfred E. Neuman; Black Spy; White Spy; Monroe |
| 24 | The Mad Guide to Man Boobs | comic story | 1 | script: Ryan Pagelow; pencils: Drew Friedman; inks: Drew Friedman | |
| 25 | What Horrible Blight Has Terrorized Americans Relentlessly? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | Alfred E. Neuman |
| 26 | Drawn-Out Dramas | comic story | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 27 | Mad Factoids | text story | 0 | letters: typeset | |