| 0 | - | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | |
| 1 | Why Kill Yourself? | promo (ad from the publisher) | 0.33 | pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 2 | If Celebrities Ran for Public Office | comic story | 4 | script: Arnie Kogen; pencils: Jack Rickard; inks: Jack Rickard | Steve Allen; Jack Paar; Jayne Mansfield; Zsa Zsa Gabor; Jonathan Winters [as Maude Frickert]; Oscar Levant; Cassius Clay; Charlton Heston; Hugh Hefner; Jerry Lewis |
| 3 | The Mad Safety Council's Predictions for the Upcoming Labor Day Weekend | comic story | 1 | script: Stan Hart; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 4 | Etiquette | comic story | 3 | script: William S. Gilbert; pencils: Don Martin; inks: Don Martin | |
| 5 | Strange Interludes in Everyday Life | comic story | 4 | script: Stan Hart; pencils: George Woodbridge; inks: George Woodbridge | |
| 6 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 7 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 8 | Louise Cramm's Realistic Mad Scrapbook | comic story | 3 | script: Stan Hart; pencils: Bob Clarke; inks: Bob Clarke; letters: Bob Clarke | |
| 9 | Misleading TV Titles | comic story | 4 | script: Al Jaffee; pencils: Mort Drucker; inks: Mort Drucker | The Black Spy, Charlie Chaplin, Curly Joe DeRita, Larry Fine, Henry, Moe Howard, Lyndon Johnson, Harpo Marx, The White Spy |
| 10 | The Sights and Sounds of the U.S.A. | comic story | 2 | script: Larry Siegel, Frank Jacobs; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 11 | A Mad Look at Firemen | cartoon | 3 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 12 | Scenes We'd Like to See: After the Ball | comic story | 1 | script: Don Edwing; pencils: Joe Orlando; inks: Joe Orlando | Cinderella |
| 13 | The Lighter Side of Summer Romances | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 14 | Mad "Celebrity Feature" Merchandising Gimmicks | comic story | 2 | script: Phil Hahn; pencils: Jack Rickard; inks: Jack Rickard | Burt Lancaster, Barbra Streisand First |
| 15 | An Incident at a Red Light | comic story | 1 | pencils: Wally Wood; inks: Wally Wood; letters: Wally Wood | |
| 16 | The Impressionist | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 17 | Auto Accessories We'd Like to See | comic story | 4 | script: Don Reilly; pencils: Bob Clarke; inks: Bob Clarke | |
| 18 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 19 | Mad's Teenage Idol Promoter of the Year | comic story | 5 | script: Larry Siegel; pencils: Mort Drucker; inks: Mort Drucker | Chet Huntley [as Chet Hunkley] |
| 20 | The Message | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 21 | The Next Scientific-Medical Breakthrough That Millions of Dollars Will Be Spent to Discover | cartoon | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 22 | Make Beautiful Hair Blecch | illustration | 1 | pencils: Frank Frazetta; inks: Frank Frazetta; colors: Frank Frazetta | Ringo Starr |