| 0 | - | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | Have Yourself a Political Party | promo (ad from the publisher) | 1 | pencils: George Woodbridge; inks: George Woodbridge | |
| 2 | - | table of contents | 1 | pencils: various; inks: various; letters: typeset | |
| 3 | Lose Your Self-Control | promo (ad from the publisher) | 0.7 | letters: typeset | |
| 4 | - | letters page | 1 | letters: typeset | |
| 5 | Why Kill Yourself? | promo (ad from the publisher) | 0.3 | pencils: Paul Coker; inks: Paul Coker | |
| 6 | When the Cigarette Industry Fights Back | comic story | 4 | script: Don Reilly; pencils: Jack Rickard; inks: Jack Rickard | |
| 7 | Another MAD Peek Through the Microscope | comic story | 3 | script: Phil Hahn; pencils: Bob Clarke; inks: Bob Clarke | |
| 8 | The MAD Academy Awards for Parents | comic story | 5 | script: Stan Hart; pencils: Mort Drucker; inks: Mort Drucker | |
| 9 | Alone in a Washroom for the First Time | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 10 | The MAD Drive-in Movie Primer | text story | 3 | script: Larry Siegel; pencils: George Woodbridge; inks: George Woodbridge | |
| 11 | The Lighter Side of Water Sports | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 12 | The Sights and Sounds of the U.S.A.: Hollywood, California | cartoon | 2 | script: Larry Siegel, Frank Jacobs; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 13 | World's Fair Pavilions We'd Really Like to See | comic story | 4 | script: Stan Hart; pencils: Joe Orlando; inks: Joe Orlando | |
| 14 | The Garden Swing | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | Black Spy; White Spy |
| 15 | The MAD Guide to Power Boating | comic story | 6 | script: Dick DeBartolo; pencils: Bob Clarke; inks: Bob Clarke | |
| 16 | One Fine Evening in Lovers' Lane | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 17 | Comic Strips They'd Really Like to Do | comic story | 4 | script: Charles M. Schulz, Walt Kelly, Ken Ernst, Allen Saunders, M. Walker, Mell Lazarus; pencils: Charles M. Schulz, Walt Kelly, Ken Ernst, Allen Saunders, M. Walker, Mell Lazarus; inks: Charles M. Schulz, Walt Kelly, Ken Ernst, Allen Saunders, M. Walker, Mell Lazarus; letters: Charles M. Schulz, Walt Kelly, Ken Ernst, Allen Saunders, M. Walker, Mell Lazarus | Charlie Brown (cameo); Pogo (cameo); Mary Worth (cameo); Beetle Bailey (cameo); Sergeant Snorkel (cameo); Miss Peach (cameo) |
| 18 | The French Disconnection | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | Black Spy; White Spy; Grey Spy |
| 19 | The Phewgitive | comic story | 5 | script: Stan Hart; pencils: Mort Drucker; inks: Mort Drucker | David Janssen [as Dr. Richard Thimble]; a local police chief and his daughter; Adolf Hitler (cameo); the head of the Olympic Committee; the man looking for Richard Thimble for weeks; a one-armed man |
| 20 | The Private Eye | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 21 | The One Sure Thing We'll All Get Out of Our Moon Shot | cartoon | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 22 | - | photo story | 1 | pencils: Lester Krauss; inks: Lester Krauss; colors: Lester Krauss | |