| 0 | - | cover | 1 | pencils: Richard Williams; inks: Richard Williams | Alfred E. Neuman |
| 1 | Twinge | comic story | 4 | script: Stan Hart; pencils: Mort Drucker; inks: Mort Drucker | Arnold Schwarzenegger [as Vonce Benediction]; Danny DeVito [as Juiceless Benediction]; Dr. Charles Nemeroff |
| 2 | A Mad Look at Self-Defense | comic story | 2 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 3 | New Comic Book Superheroes Based on Real People | comic story | 4 | script: Mike Snider; pencils: Angelo Torres; inks: Angelo Torres | Defenders of Hypocrisy [Jimmy Swaggert; Oral Roberts; Jim Bakker; Pat Robertson]; The Drudge [Roseanne Barr]; Spastic Man [Bob Goldthwait]; 19th Century Man [P.W. Botha]; Self-Destructo [Mike Tyson]; Necro Man [Elvis Presley]; The Smile [Mary Hart]; Teen-Age Mutant Kid Show Host [Pee-Wee Herman]; Ca |
| 4 | The Star Wars Defense System Can’t Fail! | comic story | 2 | script: John S. Marshall; pencils: Paul Coker; inks: Paul Coker | |
| 5 | Leather Clothes Must Be Worn | comic story | 2 | script: Frank Jacobs; pencils: Jack Davis; inks: Jack Davis | |
| 6 | Mad Switcheroos | activity | 2 | script: Frank Jacobs; pencils: Al Jaffee; inks: Al Jaffee | |
| 7 | A Mad Guide to Lesser-Known Hollywood Tourist Traps | comic story | 2 | script: Mike Snider; pencils: Bob Jones; inks: Bob Jones | |
| 8 | Mad’s Heavy Metal Quiz | activity | 2 | script: Chris Hart; pencils: Rick Tulka; inks: Rick Tulka | |
| 9 | Scientific Advances that Unimprove Our Lives! | comic story | 2 | script: Tom Koch; pencils: George Woodbridge; inks: George Woodbridge | |
| 10 | The Diabolical Dungeon Deception | comic story | 1 | script: Duck Edwing; pencils: Duck Edwing; inks: Duck Edwing | |
| 11 | Lurking Girl | comic story | 4 | script: Frank Jacobs; pencils: Angelo Torres; inks: Angelo Torres | Melanie Griffith [as Tush Megillah]; Harrison Ford [as Junk Trader]; Sigourney Weaver [as Carrion Barker]; Ivan Boesky (cameo); Alec Baldwin [as Muck]; Olympia Dukakis [as Personnel Director] (cameo); Philip Bosco [as Trash] |
| 12 | Spy vs. Spy | comic story | 1 | script: Don Edwing; pencils: Bob Clarke; inks: Bob Clarke | The Black Spy; the White Spy |
| 13 | Mad’s Cheap and Painless Methods for… Overcoming Baldness …at Little Expense and Even Less Pain | comic story | 2 | script: Paul Peter Porges; pencils: Paul Peter Porges; inks: Paul Peter Porges | |
| 14 | The Lighter Side of... | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 15 | Deceptive Ways to Junk Mail Senders to Excitedly Open Your Reply! | text story | 2 | script: Dick DeBartolo; letters: Gaspar Saladino | |
| 16 | The Ghastly Gallows Goodbye | comic story | 1 | script: Duck Edwing; pencils: Duck Edwing; inks: Duck Edwing; letters: Don Edwing | |
| 17 | Dreary John… | comic story | 5 | script: Dick DeBartolo; pencils: Sam Viviano; inks: Sam Viviano | Jane Carr [as L. Sleaze]; Jere Burns [as Curt]; Harry Groener [as Raff]; Isabelle Hofmann [as Bate]; Jugg Hurtz [as John Racy]; Father Fleece; |
| 18 | The Inconceivable Island Incident | comic story | 1 | script: Duck Edwing; pencils: Duck Edwing; inks: Duck Edwing | |
| 19 | What New Exam Will Every Student Soon Be Required to Pass? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |