| 0 | - | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | Ditched in the South Pacific | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin; colors: Don Martin | |
| 2 | - | letters page | 1 | script: Jerry De Fuccio | |
| 3 | Why Not Have the Next Issue Sent Directly to Your Home? | promo (ad from the publisher) | 0.5 | pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 4 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 5 | Midnight Wowboy | comic story | 7 | script: Stan Hart; pencils: Mort Drucker; inks: Mort Drucker | Jon Voight [as Joe Cluck]; Dustin Hoffman [as Ratface Ratfink [Ruggerio Ruccici]; John Lindsay; John McGiver [as the Salvation Army leader]; Brenda Vaccaro [as Shirley] |
| 6 | The Fitting | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 7 | Mad's Frozen Foods That Fake-Out Fresh | photo story | 3 | script: Sy Reit; pencils: Irving Schild; inks: Irving Schild | |
| 8 | Progress | comic story | 1 | script: Max Brandel; pencils: Bob Clarke; inks: Bob Clarke | |
| 9 | Spray Can Sprays We'd Like to See | comic story | 2 | script: Stan Hart; pencils: George Woodbridge; inks: George Woodbridge | |
| 10 | The Lighter Side of Money | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 11 | Joke & Dagger Dept. | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 12 | I Remember, I Remember the Wondrous Woodstock Music Fair | comic story | 3 | script: Frank Jacobs; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 13 | "The Ghost and The Mrs." Misses | comic story | 6 | script: Dick DeBartolo; pencils: Mort Drucker; inks: Mort Drucker | Hope Lange [as Mrs. Demure]; Edward Mulhare [as Captain Grogg]; Reta Shaw [as Martyr]; Charles Nelson Reilly [as Claymorgue Grogg] |
| 14 | Joke & Dagger Dept. | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 15 | Hints For Special Occasion Gifts | comic story | 2 | script: Tom Koch | |
| 16 | You Know You're Really On Your Own When... | comic story | 2 | script: Tom Koch, Gloria L. Rich; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 17 | Ads We Can Look For After the Next Successful Space Mission | comic story | 3 | script: Dick DeBartolo; pencils: Bob Clarke; inks: Bob Clarke | |
| 18 | One Night at the Fights | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 19 | Mad's Up-Dated Modern Day Mother Goose | comic story | 5 | script: Frank Jacobs; pencils: Jack Davis; inks: Jack Davis | Spiro Agnew; Joe Namath; Pete Rozelle; Hugh Hefner; Tiny Tim; Gamel Abdul Nasser; The Beatles [John Lennon; Paul McCartney; George Harrison; Ringo Starr]; Jack Benny; Mickey Rooney; Andy Warhol; Jane Fonda; Aristotle Onassis; Jacqueline Kennedy Onassis; Dr. Timothy Leary; Warren Beatty; Johnny Carso |
| 20 | What Offensive Animal Would Many Americans Like To See Become Extinct? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 21 | - | comic story | 1 | script: Chevy Chase; pencils: John Cullen Murphy; inks: John Cullen Murphy; colors: John Cullen Murphy | Peter Graves [as James Phelps] |