| 0 | Messiah Complex, Chapter Three | cover | 1 | pencils: David Finch; inks: Danny Miki; colors: Frank D'Armata | X-Factor [Multiple Man [Jamie Madrox]; Layla Miller] |
| 1 | Previously in Messiah Complex... | recap | 1 | letters: typeset | |
| 2 | Messiah Complex, Chapter Three | comic story | 22 | script: Peter David; pencils: Scot Eaton; inks: John Dell; colors: Frank D'Armata; letters: Cory Petit | X-Factor [Multiple Man [Jamie Madrox]; Layla Miller; Rictor [Julio Esteban Richter; also as Joaquin Murrieta]; Siryn [Theresa Rourke Cassidy]; Wolfsbane [Rahne Sinclair]]; Forge; X-Men [Cyclops [Scott Summers]; Nightcrawler [Kurt Wagner]; Storm [Ororo Munroe]; Wolverine [Logan; James Howlett]]; New |
| 3 | U.S. Postal Service Statement of Ownership, Management and Circulation | statement of ownership | 0.33 | letters: typeset | |
| 4 | Fury's Files | text article | 1 | pencils: Jack Kirby, John Cassaday, David Finch, Billy Tan | Angel, Beast, Beast, Cyclops, Bobby Drake, Jean Grey, Iceman, Laura Kinney, Erik Lehnsherr, Magneto, Hank McCoy, Scott Summers, Warren Worthington III, X-23 |
| 5 | Look Who's Talking: Writer Matt Fraction | text article | 1 | script: Matt Fraction, Marvel Staff; pencils: David Aja; inks: David Aja; colors: Matt Hollingsworth | Iron Fist, Danny Rand |
| 6 | Questions That Need Answers! | text article | 1 | pencils: John Cassaday, David Finch, John Romita, Bryan Hitch, Frank Cho, Mike Allred | Wasp; Kitty Pryde; Spider Woman [Jessica Drew]; Luke Cage; Psylocke; Mary Jane Watson; Squirrel Girl; Ms. Marvel; Dead Girl; Galactus; Clea; Mystique; Gambit |
| 7 | And a Sneak Peek of Things to Come... | promo (ad from the publisher) | 1 | pencils: David Finch; inks: Danny Miki | Wolverine; Rogue; Gambit; Emma Frost [White Queen]; Mr. Sinister; Lady Deathstrike |