| 0 | - | cover | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Neeraj Menon | Miles Morales, Spider-Man, Starling, Tiana Toomes |
| 1 | - | promo (ad from the publisher) | 1 | letters: typeset | |
| 2 | - | credits, title page | 3 | letters: typeset | |
| 3 | #21 Black & White Big Marvels Variant | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young | |
| 4 | #21 Big Marvels Variant | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young; colors: Skottie Young | |
| 5 | #22 Variant | cover reprint (on interior page) | 0.25 | pencils: Rose Besch; inks: Rose Besch; colors: Rose Besch | |
| 6 | #22 SDCC Giveaway Variant | cover reprint (on interior page) | 0.25 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Federico Vicentini | |
| 7 | 21 | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Matt Milla | Blade, Eric Brooks, Miles Morales, Spider-Man |
| 8 | Blood Hunt: Part 1 | comic story | 20 | script: Cody Ziglar; pencils: Brent Peeples, Daniel Picciotto; inks: Brent Peeples, Daniel Picciotto; colors: Bryan Valenza; letters: VC's Cory Petit | Blade, Bloodline, Brielle Brooks, Eric Brooks, Dracula, Hightail, Miles Morales, R'ym'r, Sandra Santos, Spider-Man |
| 9 | 22 | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Neeraj Menon | Miles Morales, Spider-Man |
| 10 | - | comic story | 20 | script: Cody Ziglar; pencils: Brent Peeples, Daniel Picciotto; inks: Brent Peeples, Daniel Picciotto; colors: Bryan Valenza; letters: VC's Cory Petit | Bloodline, Brielle Brooks, Dracula, Hightail, Miles Morales, R'ym'r, Sandra Santos, Spider-Man |
| 11 | - | blank page(s) | 1 | | |
| 12 | Annual 1 | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Erick Arciniega | Miles Morales, Spider-Man |
| 13 | Night Shift | comic story | 4 | script: Danny Lore; pencils: Elena Casagrande; inks: Elena Casagrande; colors: Dee Cunniffe; letters: VC's Cory Petit | Bloodline, Brielle Brooks, Miles Morales, Spider-Man |
| 14 | 23 | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Neeraj Menon | Miles Morales, Spider-Man, Starling, Tiana Toomes |
| 15 | Birds of a Feather: Part One | comic story | 20 | script: Cody Ziglar; pencils: Federico Vicentini; inks: Federico Vicentini; colors: Bryan Valenza; letters: VC's Cory Petit | Doc Sasquatch, Keisha Kwan, Miles Morales, Leonard Samson, Spider-Man, Starling, Adrian Toomes, Tiana Toomes, The Vulture, Zip Zephyr |
| 16 | 24 | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Neeraj Menon | Miles Morales, Spider-Man, Adrian Toomes, The Vulture |
| 17 | Birds of a Feather: Part Two | comic story | 20 | script: Cody Ziglar; pencils: Federico Vicentini; inks: Federico Vicentini; colors: Bryan Valenza; letters: VC's Cory Petit | Black Panther, Misty Knight, Keisha Kwan, Miles Morales, Spider-Man, Starling, T'Challa, Adrian Toomes, Tiana Toomes, The Vulture |
| 18 | 25 | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Neeraj Menon | Black Panther, Miles Morales, Spider-Man, T'Challa |
| 19 | Birds of a Feather: Part Three | comic story | 20 | script: Cody Ziglar; pencils: Federico Vicentini; inks: Federico Vicentini; colors: Bryan Valenza; letters: VC's Cory Petit | Black Panther, Misty Knight, Keisha Kwan, Miles Morales, Spider-Man, Starling, T'Challa, Adrian Toomes, Tiana Toomes, The Vulture |
| 20 | #22 Deadpool Kills the Marvel Universe Variant | cover reprint (on interior page) | 1 | pencils: Ron Lim; inks: Ron Lim; colors: Israel Silva | |
| 21 | 26 | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Neeraj Menon | Miles Morales, Spider-Man |
| 22 | Birds of a Feather: Part Four | comic story | 20 | script: Cody Ziglar; pencils: Federico Vicentini; inks: Federico Vicentini; colors: Bryan Valenza; letters: VC's Cory Petit | Black Panther, Misty Knight, Keisha Kwan, Miles Morales, Spider-Man, Starling, T'Challa, Adrian Toomes, Tiana Toomes, The Vulture |
| 23 | Annual Variant | cover reprint (on interior page) | 1 | pencils: Dike Ruan; inks: Dike Ruan; colors: Moreno Dinisio | |
| 24 | #23 Disco Dazzler Variant | cover reprint (on interior page) | 1 | pencils: Karen S. Darboe; inks: Karen S. Darboe; colors: Jesus Aburtov | |
| 25 | #23 Variant | cover reprint (on interior page) | 0.5 | pencils: Doaly; inks: Doaly; colors: Doaly | |
| 26 | #24 Stormbreakers Variant | cover reprint (on interior page) | 0.25 | pencils: Nic Klein; inks: Nic Klein; colors: Nic Klein | |
| 27 | #25 Doom Variant | cover reprint (on interior page) | 0.25 | pencils: Annie Wu; inks: Annie Wu; colors: Annie Wu | |
| 28 | #25 New Costume Variant | cover reprint (on interior page) | 1 | pencils: Mateus Manhanini; inks: Mateus Manhanini; colors: Mateus Manhanini | |
| 29 | #25 Design Variant | cover reprint (on interior page) | 1 | pencils: Federico Vicentini; inks: Federico Vicentini; colors: Federico Vicentini | |
| 30 | #25 Variant | cover reprint (on interior page) | 1 | pencils: Sara Pichelli; inks: Sara Pichelli; colors: Matthew Wilson | |
| 31 | #26 Marvel Two-In-One Variant | cover reprint (on interior page) | 1 | pencils: Amanda Conner; inks: Amanda Conner; colors: Paul Mounts | |
| 32 | - | promo (ad from the publisher) | 1 | letters: typeset | |
| 33 | - | promo (ad from the publisher) | 1 | letters: typeset | |