| 0 | - | cover | 1 | pencils: Alan Davis; inks: Mark Farmer; colors: Javier Rodríguez | Doctor Doom, Victor Von Doom, Ben Grimm, Mister Fantastic, Nathaniel Richards, Reed Richards, The Thing |
| 1 | The World's Greatest Comic Magazine | blank page(s) | 1 | script: Stan Lee | |
| 2 | - | credits, title page | 2 | pencils: Neil Edwards; inks: Paul Neary; colors: Paul Mounts | evil Nathaniel Richards |
| 3 | There Is Always Hope | illustration | 2 | script: Jonathan Hickman; pencils: Neil Edwards; inks: Scott Hanna | future Franklin Richards; future Valeria Richards |
| 4 | The Future Foundation | illustration | 2 | pencils: Neil Edwards; inks: Andrew Currie; colors: Paul Mounts | The Wizard |
| 5 | I Teach One Class and It's Pass or Fail | cover reprint (on interior page) | 1 | script: Jonathan Hickman; pencils: Alan Davis; inks: Mark Farmer, Javier Rodríguez | Mr. Fantastic |
| 6 | The Future Foundation | comic story | 22 | script: Jonathan Hickman; pencils: Neil Edwards; inks: Andrew Currie; colors: Paul Mounts; letters: Rus Wooton | Mr. Fantastic; She-Hulk; Alex Powers; Invisible Woman; Old Atlanteans; Spider-Man; Turg; Korr; Mik; Tong; Ted Castle; Alex Ultron; Natalie X; Lightwave; Robert Bruce Banner, Jr.; Franklin Richards; Human Torch; the Thing; Valeria Richards; Dragon Man; Artie; Leech; Wizard |
| 7 | 4 | blank page(s) | 1 | | |
| 8 | I'll Take It | illustration | 1 | script: Jonathan Hickman; pencils: Alan Davis; inks: Mark Farmer | Human Torch [Johnny Storm]; Arcade; Franklin Richards |
| 9 | The Frank-tastic Four | comic story | 22 | script: Jonathan Hickman; pencils: Neil Edwards; inks: Andrew Currie; colors: Paul Mounts; letters: Rus Wooton | Leech; Franklin Richards; Mr. Fantastic; Dragon Man; Mik; Valeria Richards; Human Torch; Arcade; Impossible Man; Alissa Moy; Ted Castle; Alex Ultron; Natalie X; Lightwave; Robert Bruce Banner, Jr.; the Thing; Turg; Korr; Tong; Alex Power |
| 10 | 4 | blank page(s) | 1 | | |
| 11 | From Here We Go Onward and Boldly | illustration | 1 | script: Jonathan Hickman; pencils: Alan Davis; inks: Mark Farmer | Reed Richards [Mr. Fantastic]; Ben Grimm [the Thing]; Victor Von Doom [Dr. Doom]; Nathaniel Richards |
| 12 | When Everything's Lost, the Battle Is Won... | comic story | 22 | script: Jonathan Hickman; pencils: Neil Edwards; inks: Paul Neary; colors: Paul Mounts; letters: VC, Rus Wooton | future Franklin Richards; future Valeria Richards; Nathaniel Richards; Reed Richards [Mr. Fantastic] (flashback); Victor Von Doom [Dr. Doom] (flashback); Ben Grimm [the Thing] (flashback); Immortus (flashback); Invisible Woman; Night Machine (cameo flashback); Howard Stark (cameo flashback); alterna |
| 13 | 4 | blank page(s) | 1 | | |
| 14 | Every Boy Deserves a Father | illustration | 2 | script: Jonathan Hickman; pencils: Alan Davis; inks: Mark Farmer | Mr. Fantastic; the Thing; Dr. Doom; Nathaniel Richards |
| 15 | ... Because of All These Things I've Done. | comic story | 25 | script: Jonathan Hickman; pencils: Neil Edwards; inks: Scott Hanna; colors: Paul Mounts; letters: Rus Wooton | Reed Richards; Ben Grimm; Nathaniel Richards; alternate Nathaniel Richards; Victor Von Doom; Anachronauts; Invisible Woman; future Valeria Richards; future Franklin Richards |
| 16 | Cover Gallery | blank page(s) | 1 | letters: typeset | |
| 17 | - | cover reprint (on interior page) | 1 | pencils: Alan Davis; inks: Mark Farmer; colors: Javier Rodríguez | Mr. Fantastic |
| 18 | - | cover reprint (on interior page) | 1 | pencils: Alan Davis; inks: Mark Farmer; colors: Javier Rodríguez | Human Torch [Johnny Storm]; Arcade; Franklin Richards |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Alan Davis; inks: Mark Farmer; colors: Javier Rodríguez | Reed Richards [Mr. Fantastic]; Ben Grimm [the Thing]; Victor Von Doom [Dr. Doom]; Nathaniel Richards |
| 20 | - | cover reprint (on interior page) | 1 | pencils: Alan Davis; inks: Mark Farmer; colors: Javier Rodríguez | Mr. Fantastic; the Thing; Victor von Doom; Nathaniel Richards |
| 21 | - | cover reprint (on interior page) | 1 | pencils: John Tyler Christopher; inks: John Tyler Christopher; colors: John Tyler Christopher | |
| 22 | - | promo (ad from the publisher) | 1 | pencils: Alan Davis; inks: Mark Farmer | |