| 0 | - | cover | 1 | pencils: Kaare Andrews; inks: Kaare Andrews; colors: Kaare Andrews | Captain America; Spider-Man; Quicksilver; Iron Man; Deadpool |
| 1 | Collected Editions | promo (ad from the publisher) | 1 | letters: typeset | |
| 2 | - | illustration | 1 | pencils: Dalibor Talajić; inks: Dalibor Talajić; colors: Lee Loughridge | Deadpool |
| 3 | - | credits, title page | 2 | pencils: Dalibor Talajić; inks: Dalibor Talajić; colors: Lee Loughridge | |
| 4 | Deadpool Kills the Marvel Universe #1 | cover reprint (on interior page) | 1 | pencils: Kaare Andrews; inks: Kaare Andrews; colors: Kaare Andrews | Captain America; Spider-Man; Quicksilver; Iron Man; Deadpool |
| 5 | - | comic story | 20 | script: Cullen Bunn; pencils: Dalibor Talajić; inks: Dalibor Talajić; colors: Lee Loughridge; letters: VC, Joe Sabino | Deadpool; Watcher; Fantastic Four [Sue Richards; Reed Richards; Johnny Storm]; Psycho-Man [Dr. Benjamin Brighton]; X-Men [Professor Xavier; Storm; Cyclops; Wolverine]; Green Goblin (cameo); Dr. Doom (cameo); Sandman (cameo); Hammerhead (cameo); Vulture (cameo); Maron Mordo (cameo); Mysterio (cameo); |
| 6 | Deadpool Kills the Marvel Universe #2 | cover reprint (on interior page) | 1 | pencils: Kaare Andrews; inks: Kaare Andrews; colors: Kaare Andrews | Deadpool; Spider-Woman; Daredevil; Hulk; Captain America; Thor |
| 7 | - | comic story | 20 | script: Cullen Bunn; pencils: Dalibor Talajić; inks: Dalibor Talajić; colors: Lee Loughridge; letters: VC, Joe Sabino | Deadpool; Trish Tilby; Spider-Man; Ghost Rider (cameo); Dr. Doom (cameo); Howard the Duck (cameo); Avengers [Iron Man; Captain America; Captain Marvel; Thor; Spider-Woman; Hawkeye; Luke Cage; Wolverine]; Jarvis; Hulk; Alicia Masters; Rick Jones; May Parker; Mary Jane Watson; Taskmaster |
| 8 | Deadpool Kills the Marvel Universe #3 | cover reprint (on interior page) | 1 | pencils: Kaare Andrews; inks: Kaare Andrews; colors: Kaare Andrews | Deadpool |
| 9 | Been on Deadpool's trail for days now. | comic story | 20 | script: Cullen Bunn; pencils: Dalibor Talajić; inks: Dalibor Talajić; colors: Lee Loughridge; letters: VC, Joe Sabino | Deadpool; Venom (cameo); Jamie Madrox (cameo); Hobgoblin (cameo); Taskmaster; X-Men [Professor Xavier; Cyclops; Pixie; Rogue; Gambit; Colossus; Emma Frost; Cannonball; Magneto; Kitty Pryde; Wolverine; X-23; Daken]; Arcade; Dr. Strange (cameo); Wong (cameo) |
| 10 | Deadpool Kills the Marvel Universe #4 | cover reprint (on interior page) | 1 | pencils: Kaare Andrews; inks: Kaare Andrews; colors: Kaare Andrews | Deadpool; Punisher |
| 11 | - | comic story | 20 | script: Cullen Bunn; pencils: Dalibor Talajić; inks: Dalibor Talajić; colors: Lee Loughridge; letters: VC, Joe Sabino | Deadpool; Black Knight (cameo); Dr. Octopus (cameo); Black Widow (cameo); Shocker (cameo); Daredevil (cameo); Kingpin (cameo); Nick Fury (cameo); Punisher; Puppet Master; Thanos (cameo); Taskmaster; Man-Thing; Cullen Bunn; Dalibor Talajić |
| 12 | - | text story | 5 | script: Cullen Bunn | |
| 13 | - | illustration | 1 | pencils: Dalibor Talajić; inks: Dalibor Talajić | |
| 14 | Cover Sketches | illustration | 3 | pencils: Kaare Andrews; inks: Kaare Andrews; colors: Kaare Andrews | |