| 0 | - | cover | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool |
| 1 | - | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool [Wade Wilson] |
| 2 | In Wade We Trust | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Deadpool; mad necromancer S.H.I.E.L.D. agent; Captain America; Harry S. Truman; S.H.I.E.L.D. agent Emily Preston; S.H.I.E.L.D. agent Gorman; giant mutated lizard creature; Thor; Franklin D. Roosevelt; George Washington; Abraham Lincoln; Jimmy Carter; dead Presidents of the United States; Gerald Ford |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool |
| 4 | We Fought a Zoo | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Deadpool; Benjamin Franklin; George Washington; John Kennedy; mad necromancer S.H.I.E.L.D. agent; Preston; S.H.I.E.L.D. Agent Gorman; Theodore Roosevelt; Wong; Doctor Strange |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool [Wade Wilson]; Richard Nixon; Checkers |
| 6 | Dr. Strange Lives | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Deadpool; Doctor Strange; Wong; Benjamin Franklin; Preston; Michael (mad necromancer S.H.I.E.L.D. agent); Richard Nixon; George Washington; Abraham Lincoln; Gerald Ford |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool; Abraham Lincoln (zombie) |
| 8 | The Quick and the Dead and the Really Dead | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Deadpool; John Fitzgerald Kennedy; S.H.I.E.L.D. agent Emily Preston; Benjamin Franklin; James Polk; John Tyler; Zachary Taylor; Millard Fillmore; Herbert Hoover; Calvin Coolidge; Warren Harding; James Buchanan; John Adams; John Quincy Adams; Abraham Lincoln; Martin Van Buren; Andrew Jackson; Frankli |
| 9 | - | cover reprint (on interior page) | 1 | pencils: Geof Darrow; inks: Geof Darrow; colors: Peter Doherty | Deadpool |
| 10 | Star Wars: Revenge of the Gipper | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Joe Sabino | Benjamin Franklin's ghost; Deadpool; Michael (mad necromancer S.H.I.E.L.D. agent); Emily Preston (dies); Ronald Reagan; George Washington; Lyndon Johnson |
| 11 | - | cover reprint (on interior page) | 1 | pencils: Skottie Young; inks: Skottie Young; colors: Skottie Young | Deadpool [Wade Wilson] |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Zachary Baldus; inks: Zachary Baldus; colors: Zachary Baldus | Deadpool; George Washington (zombie) |
| 13 | National Maul | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Tony Moore; inks: Tony Moore; colors: Val Staples; letters: Clayton Cowles | Deadpool; Michael (mad necromancer S.H.I.E.L.D. agent); Emily Preston (dead, ghost); George Washington; Abraham Lincoln; William Howard Taft; Scott Adsit; James Monroe; Thomas Jefferson; James Madison; William Henry Harrison; Ulysses Grant; Lyndon Johnson; Rutherford B. Hayes; Dwight D. Eisenhower; |
| 14 | - | cover reprint (on interior page) | 1 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Deadpool [Wade Wilson] |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Kevin Maguire; inks: Kevin Maguire; colors: Rosemary Cheetham | Deadpool; Tony Stark [Iron Man] |
| 16 | Drinking Game | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Scott Koblish; inks: Scott Koblish; colors: Val Staples; letters: Joe Sabino | Ben Urich; Joe Robertson; Jonah Jameson; Peter Parker; Dubowsky; Deadpool; Flash Thompson; Alex Power; Julie Power; Katie Power; Jack Power; Vetis; Angar; Iron Man [Tony Stark]; Mephisto; Cable |
| 17 | Dear Deadpool | letters page | 1 | script: Gerry Duggan, Brian Posehn | |
| 18 | - | cover reprint (on interior page) | 1 | pencils: Arthur Adams; inks: Arthur Adams; colors: Peter Steigerwald | Deadpool |
| 19 | Running with the Devil | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Mike Hawthorne; inks: Mike Hawthorne; colors: Val Staples; letters: Joe Sabino | Deadpool; Emily Preston (ghost); Jeff Preston; Shane Preston; Vetis; Michael (mad necromancer S.H.I.E.L.D. agent); Benjamin Franklin (ghost); Corrado Coloruno |
| 20 | - | cover reprint (on interior page) | 1 | pencils: Tony Moore; inks: Tony Moore; colors: Tony Moore | Deadpool [Wade Wilson] |
| 21 | - | cover reprint (on interior page) | 1 | pencils: Arthur Adams; inks: Arthur Adams; colors: Peter Steigerwald | Deadpool |
| 22 | The Devil and the Deep Blue Sea | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Mike Hawthorne; inks: Mike Hawthorne; colors: Val Staples; letters: Joe Sabino | Deadpool; Emily Preston (ghost); Michael (mad necromancer S.H.I.E.L.D. agent); Benjamin Franklin (ghost); Vetis |
| 23 | - | cover reprint (on interior page) | 1 | pencils: Tradd Moore; inks: Tradd Moore; colors: Edgar Delgado | Deadpool; Spider-Man [Superior Spider-Man; Otto Octavius] |
| 24 | Eight Legs to Kill You | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Mike Hawthorne; inks: Mike Hawthorne; colors: Val Staples; letters: Joe Sabino | Deadpool; Benjamin Franklin (ghost); Emily Preston (ghost); Michael (mad necromancer S.H.I.E.L.D. agent, spirit); Spider-Man [Otto Octavius]; Batroc; Daniel Gump (introduction, death); Trapster; Taskmaster; Chance; Lady Stilt Man |
| 25 | - | cover reprint (on interior page) | 1 | pencils: Matthew Waite; inks: Matthew Waite; colors: Matthew Waite; letters: Matthew Waite | Deadpool |
| 26 | - | cover reprint (on interior page) | 1 | pencils: Tradd Moore; inks: Tradd Moore; colors: Edgar Delgado | Deadpool; Luke Cage [Power Man]; Black Widow; Daredevil |
| 27 | Dare to Be Deviled | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Mike Hawthorne; inks: Mike Hawthorne; colors: Val Staples; letters: Joe Sabino | Deadpool; Emily Preston (ghost); Terrence Preston; Terrence Preston Junior; Scott Adsit; Benjamin Franklin (ghost); Michael (mad necromancer S.H.I.E.L.D. agent, spirit); Mephisto; Jessica Jones; The Blender [Bobby Tisdell] (death); Daredevil; Vetis |
| 28 | - | cover reprint (on interior page) | 1 | pencils: Tradd Moore; inks: Tradd Moore; colors: Marte Gracia | Deadpool; Mephisto |
| 29 | Damned If You Win, Damned If You Lose | comic story | 20 | script: Gerry Duggan, Brian Posehn; pencils: Mike Hawthorne; inks: Mike Hawthorne, Jason Gorder, John Lucas; colors: Val Staples; letters: Joe Sabino | Deadpool; Agent Preston; Vetis; H.E.R.B.I.E.; Michael (mad necromancer S.H.I.E.L.D. agent); Mephisto; Benjamin Franklin's ghost |
| 30 | - | cover reprint (on interior page) | 0.25 | pencils: Carlo Barberi; inks: Carlo Barberi; colors: Edgar Delgado | Deadpool [Wade Wilson] |
| 31 | - | cover reprint (on interior page) | 0.25 | pencils: Charles Paul Wilson III; inks: Charles Paul Wilson III; colors: Charles Paul Wilson III | Deadpool [Wade Wilson] |
| 32 | - | cover reprint (on interior page) | 0.25 | pencils: Tradd Moore; inks: Tradd Moore; colors: Marte Gracia | Deadpool [Wade Wilson] |
| 33 | - | cover reprint (on interior page) | 0.25 | pencils: Gurihiru; inks: Gurihiru; colors: Gurihiru | Deadpool [Wade Wilson] |
| 34 | - | cover reprint (on interior page) | 0.25 | pencils: Daniel Acuña; inks: Daniel Acuña; colors: Daniel Acuña | Deadpool; Doctor Strange |
| 35 | - | cover reprint (on interior page) | 0.25 | pencils: Tradd Moore; inks: Tradd Moore; colors: Marte Gracia | Deadpool; Abraham Lincoln (zombie) |
| 36 | - | cover reprint (on interior page) | 0.25 | pencils: Giuseppe Camuncoli; inks: Giuseppe Camuncoli; colors: Marte Gracia | Deadpool [Wade Wilson] |
| 37 | - | cover reprint (on interior page) | 0.25 | pencils: Adam Warren; inks: Adam Warren; colors: Guru eFX | Deadpool; George Washington (zombie) |
| 38 | Dear Deadpool | letters page | 7 | script: Gerry Duggan, Brian Posehn | |
| 39 | Deadpool #7 | text story | 10 | script: Gerry Duggan, Brian Posehn; pencils: Scott Koblish; inks: Scott Koblish | |