| 0 | - | cover | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Black Widow, Natasha Romanoff |
| 1 | - | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Black Widow, Natasha Romanoff |
| 2 | The Ties That Bind Part 1 | comic story | 20 | script: Kelly Thompson; pencils: Elena Casagrande; inks: Elena Casagrande; colors: Jordie Bellaire; letters: VC's Cory Petit | Arcade, Bucky Barnes, Clint Barton, Black Widow, Captain America, Hawkeye, Steve Rogers, Natasha Romanoff, Winter Soldier |
| 3 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Travis Charest; inks: Travis Charest; colors: Travis Charest | Black Widow, Natasha Romanoff |
| 4 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: J. G. Jones; inks: J. G. Jones; colors: Dave McCaig | Black Widow, Natasha Romanoff |
| 5 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Kim Jacinto; inks: Kim Jacinto; colors: Tamra Bonvillain | Black Widow, Natasha Romanoff |
| 6 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: Gerald Parel; inks: Gerald Parel; colors: Gerald Parel | Black Widow, Natasha Romanoff |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Black Widow, Natasha Romanoff |
| 8 | The Ties That Bind Part 2 | comic story | 20 | script: Kelly Thompson; pencils: Elena Casagrande; inks: Elena Casagrande; colors: Jordie Bellaire; letters: VC's Cory Petit | Black Widow, Natasha Romanoff |
| 9 | #1 Variant | cover reprint (on interior page) | 0.25 | pencils: J. Scott Campbell; inks: J. Scott Campbell; colors: Sabine Rich | Black Widow, Natasha Romanoff |
| 10 | #2 Variant | cover reprint (on interior page) | 0.25 | pencils: J. Scott Campbell; inks: J. Scott Campbell; colors: Sabine Rich | Yelena Belova |
| 11 | #2 Variant | cover reprint (on interior page) | 0.25 | pencils: Mattia De Iulis; inks: Mattia De Iulis; colors: Mattia De Iulis | Black Widow, Natasha Romanoff |
| 12 | #2 Variant | cover reprint (on interior page) | 0.25 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Black Widow, Natasha Romanoff |
| 13 | - | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Black Widow, Natasha Romanoff |
| 14 | The Ties That Bind Part 3 | comic story | 20 | script: Kelly Thompson; pencils: Elena Casagrande; inks: Elena Casagrande; colors: Jordie Bellaire; letters: VC's Cory Petit | Black Widow, Natasha Romanoff |
| 15 | #2 Horror Variant | cover reprint (on interior page) | 0.25 | pencils: Joshua Swaby; inks: Joshua Swaby; colors: Joshua Swaby | Bucky Barnes, Black Widow, Natasha Romanoff, Winter Soldier |
| 16 | #2 Variant | cover reprint (on interior page) | 0.25 | pencils: Takashi Okazaki; inks: Takashi Okazaki; colors: Jordie Bellaire | Black Widow, Natasha Romanoff |
| 17 | #3 Variant | cover reprint (on interior page) | 0.25 | pencils: Jen Bartel; inks: Jen Bartel; colors: Jen Bartel | Black Widow, Natasha Romanoff |
| 18 | #3 Variant | cover reprint (on interior page) | 0.25 | pencils: Annie Wu; inks: Annie Wu; colors: Annie Wu | Black Widow, Natasha Romanoff |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes | Black Widow, Natasha Romanoff |
| 20 | The Ties That Bind Part 4 | comic story | 20 | script: Kelly Thompson; pencils: Elena Casagrande, Carlos Gómez; inks: Elena Casagrande, Carlos Gómez; colors: Jordie Bellaire, Federico Blee; letters: VC's Cory Petit | Black Widow, Natasha Romanoff |
| 21 | #4 MCU Variant | cover reprint (on interior page) | 0.25 | pencils: Patrick Brown; inks: Patrick Brown; colors: Patrick Brown | Black Widow, Tony Masters, Taskmaster, Natasha Romanoff |
| 22 | #4 Variant | cover reprint (on interior page) | 0.25 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Marco Checchetto | Black Widow, Natasha Romanoff |
| 23 | - | cover reprint (on interior page) | 0.25 | pencils: Skan; inks: Skan; colors: Skan | Black Widow, Natasha Romanoff |
| 24 | #5 Variant | cover reprint (on interior page) | 0.25 | pencils: Olivier Coipel; inks: Olivier Coipel; colors: Olivier Coipel | Black Widow, Natasha Romanoff |
| 25 | - | cover | 1 | pencils: Adam Hughes; inks: Adam Hughes; colors: Adam Hughes; letters: Adam Hughes | Black Widow, Natasha Romanoff |
| 26 | The Ties That Bind Part 5 | comic story | 20 | script: Kelly Thompson; pencils: Elena Casagrande, Rafael de Latorre; inks: Elena Casagrande, Rafael de Latorre; colors: Jordie Bellaire; letters: VC's Cory Petit | Black Widow, Natasha Romanoff |