| 0 | - | cover | 1 | pencils: John Romita Jr.; inks: Al Milgrom | Morrie Bench, Hydro-Man, Flint Marko, Peter Parker, Sandman, Spider-Man |
| 1 | Epic Collection | promo (ad from the publisher) | 1 | letters: typeset | |
| 2 | Spider-Man: Threat or Menace? | credits, title page | 2 | letters: typeset | |
| 3 | Spider-Man: Threat or Menace? | table of contents | 1 | letters: typeset | |
| 4 | Final Curtain! | cover reprint (on interior page) | 1 | pencils: Mike Nasser; inks: Al Milgrom | Spider-Man [Peter Parker]; Mesmero |
| 5 | Mesmero's Revenge! | comic story | 17 | script: Denny O'Neil; pencils: Jim Mooney; inks: Pablo Marcos; colors: Ben Sean; letters: Jim Novak | Spider-Man [Peter Parker]; Deborah Whitman; Robbie Robertson; J. Jonah Jameson; Mesmero (villain); Gwen Stacy (cameo flashback) |
| 6 | The Amazing Spider-Man #208 | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom; letters: Gaspar Saladino | Peter Parker, Spider-Man |
| 7 | Fusion! | comic story | 17 | script: Denny O'Neil, Jim Shooter, Mark Gruenwald; pencils: John Romita Jr., Brett Breeding, Al Milgrom; inks: Brett Breeding, Al Milgrom; colors: Ben Sean; letters: Jean Simek | Lance Bannon, Barney Bushkin, Rupert Dockery, April Maye, May Parker, Peter Parker, Spider-Man |
| 8 | The Amazing Spider-Man #209 | cover reprint (on interior page) | 1 | pencils: Alan Weiss; inks: Alan Weiss | Kraven the Hunter, Sergei Kravinoff, Peter Parker, Spider-Man |
| 9 | To Salvage My Honor! | comic story | 17 | script: Denny O'Neil; pencils: Alan Weiss; inks: Janson, Bob McLeod, Rubinstein, Bob Wiacek, Milgrom, Alan Weiss; colors: Bob Sharen; letters: Mark Rogan | Barney Bushkin, Calypso, Rupert Dockery, Jessica Drew, Kraven the Hunter, Sergei Kravinoff, Peter Parker, Spider-Man, Spider-Woman, Debra Whitman |
| 10 | Spidey and Doctor Strange Versus Doctor Doom and the Dread Dormammu | cover reprint (on interior page) | 1 | pencils: Frank Miller; inks: Tom Palmer; colors: Tom Palmer | Doctor Doom, Doctor Strange, Victor Von Doom, Peter Parker, Spider-Man, Stephen Strange |
| 11 | The Book of the Vishanti | comic story | 40 | script: Denny O'Neil; pencils: Frank Miller; inks: Tom Palmer; colors: Ben Sean; letters: Joe Rosen | Lucius Dilby, Doctor Doom, Doctor Strange, Victor Von Doom, Dormammu, Adolf Hitler, Dean Jastrow, Peter Parker, Spider-Man, Stephen Strange, Debra Whitman, Wong |
| 12 | The Amazing Spider-Man #210 | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom; letters: Gaspar Saladino | Madame Web, Peter Parker, Spider-Man, Cassandra Webb |
| 13 | The Prophecy of Madame Web! | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr., Joe Sinnott; inks: Joe Sinnott; colors: B. Sharen; letters: J. Novak | Rupert Dockery, J. Jonah Jameson, Madame Web, Peter Parker, Spider-Man, Cassandra Webb, Debra Whitman |
| 14 | The Amazing Spider-Man #211 | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom; letters: Irving Watanabe | Sub-Mariner, Peter Parker, Spider-Man, Namor |
| 15 | The Spider and the Sea-Scourge! | comic story | 22 | script: Dennis O'Neil; pencils: John Romita Jr.; inks: Jim Mooney; letters: Jim Novak | May Parker, Sub-Mariner, Peter Parker, Spider-Man, Debra Whitman, Namor |
| 16 | Spidey Faces the Wet Threat of Hydro-Man! | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom; letters: Danny Crespi | Spider-Man [Peter Parker]; Hydro-Man |
| 17 | The Coming of Hydroman! | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr.; inks: Jim Mooney; colors: Bob Sharen; letters: Jim Novak | Spider-Man [Peter Parker]; Hydro-Man (1st and introducton); J. Jonah Jameson; Debbie Whitman; Robbie Robertson |
| 18 | The Amazing Spider-Man #213 | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom; letters: Michael Higgins | Spider-Man [Peter Parker]; Wizard |
| 19 | All They Want To Do Is Kill You, Spider-Man... | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr., Jim Mooney; inks: Jim Mooney; colors: Bob Sharen; letters: Jim Novak | Spider-Man [Peter Parker]; Wizard; Llyra; Debbie Whitman; Wino Charlie [Charles Fortesque Smythington IV] |
| 20 | The Amazing Spider-Man #214 | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom | Spider-Man [Peter Parker]; Frightful Four [Wizard; Llyra; Sandman; Trapster]; Namor the Sub-Mariner |
| 21 | Then Shall We Both Be Betrayed! | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr., Jim Mooney; inks: Jim Mooney; colors: Bob Sharen; letters: Jim Novak | Spider-Man [Peter Parker]; Frightful Four [Wizard; Llyra; Sandman; Trapster]; Namor the Sub-Mariner; Percy Rue; Wino Charlie [Charles Fortesque Smythington IV]; Marion Stensgard |
| 22 | The Amazing Spider-Man #215 | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom; letters: Danny Crespi | Spider-Man [Peter Parker]; Namor the Sub-Mariner; Frightful Four [Llyra; Wizard; Sandman; Trapster] |
| 23 | By My Powers Shall I be Vanquished! | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr., Jim Mooney; inks: Jim Mooney; colors: Roger Slifer; letters: Jim Novak | Spider-Man [Peter Parker]; Namor the Sub-Mariner; Frightful Four [Llyra; Wizard; Sandman; Trapster] (villain); Debbie Whitman; Lord Vashti; Fantastic Four [Invisible Girl; Mr. Fantastic; Thing] |
| 24 | The Race Is On... Will Death Be the Victor? | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom | Spider-Man [Peter Parker]; Madame Web |
| 25 | Marathon | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr., Jim Mooney; inks: Jim Mooney; colors: Bob Sharen; letters: Jim Novak | Spider-Man [Peter Parker]; Madame Web; Debbie Whitman; J. Jonah Jameson; Biff Rifkin; Gwen Stacy (cameo flashback); Mary Jane Watson (cameo flashback) |
| 26 | Here's Mud in Your Eye, Spidey! | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Al Milgrom | Morrie Bench, Hydro-Man, Flint Marko, Peter Parker, Sandman, Spider-Man |
| 27 | Here's Mud in Your Eye! | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr., Jim Mooney; inks: Jim Mooney; colors: Bob Sharen; letters: Jim Novak | Morrie Bench, Hydro-Man, Flint Marko, Peter Parker, Sandman, Spider-Man, Debra Whitman |
| 28 | In Manhattan Stalks a Monster! | cover reprint (on interior page) | 1 | pencils: Frank Miller; inks: Frank Miller; colors: Tom Smith | Spider-Man [Peter Parker]; an amalgam of Sandman and Hydro-Man |
| 29 | Eye of the Beholder! | comic story | 22 | script: Denny O'Neil; pencils: John Romita Jr.; inks: Jim Mooney, Milgrom; colors: Bob Sharen; letters: Novak | Spider-Man [Peter Parker]; Sandman [William Baker]; Hydro-Man [Morris Bench]; J. Jonah Jameson; Robbie Robertson; Sadie Frickett; Matt Murdock [Daredevil]; Foggy Nelson; Travis Rave; Debbie Whitman; Biff Rifkin |
| 30 | Peter Parker -- Criminal! | cover reprint (on interior page) | 1 | pencils: Frank Miller; inks: Frank Miller | Spider-Man; Peter Parker |
| 31 | Peter Parker -- Criminal! | comic story | 22 | script: Denny O'Neil; pencils: Luke McDonnell; inks: Jim Mooney; colors: Don Warfield; letters: Jim Novak | Spider-Man [Peter Parker]; Grey Gargoyle; Jonas Harrow; Matt Murdock [Daredevil]; Armand DuBroth; J. Jonah Jameson; Aunt May Parker; Lonesome Pinky |
| 32 | A Coffin for... the Amazing Spider-Man | cover reprint (on interior page) | 1 | pencils: Bob Layton; inks: Bob Layton; letters: Irv Watanabe | Moon Knight, Peter Parker, Marc Spector, Spider-Man |
| 33 | A Coffin for Spider-Man! | comic story | 17 | script: Michael Fleisher; pencils: Bob McLeod; inks: Bob McLeod; colors: Bob Sharen; letters: Bob McLeod | Spider-Man [Peter Parker]; Maggia; Moon Knight [Marc Spector; Steven Grant; Jake Lockley] (guest star); J. Jonah Jameson (guest star); Marlene Alraune (guest star); Jean-Paul "Frenchie" DuChamp (guest star); Blinky; Pete; Ernie; Louie Frenchetti; Weasel |
| 34 | The Nursing Home Caper | comic story | 5 | script: Mike Barr; pencils: Win Mortimer; inks: Win Mortimer; colors: Don Warfield; letters: John Morelli | Aunt May Parker; Peter Parker [Spider-Man]; Anna May Watson; Polly; Mr. Brewster; Razor; Scab; Rodney |
| 35 | Crisis on Campus! | cover reprint (on interior page) | 1 | pencils: Bob Wiacek; inks: Bob Wiacek | Spider-Man [Peter Parker]; Ramrod |
| 36 | Blues For Lonesome Pinky! | comic story | 21 | script: Denny O'Neil; pencils: Alan Kupperberg; inks: Jim Mooney; colors: C. Scheele; letters: Jim Novak | Spider-Man [Peter Parker]; Ramrod; Dean Ulrich; Mr. Pincus [Lonesome Pinky]; Debra Whitman; Biff Rifkin; Dr. Kissik |
| 37 | The Amazing Spider-Man #222 | cover reprint (on interior page) | 1 | pencils: Ed Hannigan, Walter Simonson; inks: Walter Simonson | Spider-Man [Peter Parker]; Speed Demon [James Saunders] |
| 38 | Faster Than the Eye! | comic story | 21 | script: Bill Mantlo; pencils: Bob Hall; inks: Jim Mooney; colors: Sean; letters: Parker | Spider-Man [Peter Parker]; Speed Demon [James Saunders] (first and introduction; formerly the Whizzer; changes his identity); J. Jonah Jameson; Lance Bannon; Robbie Robertson; CAMEO FLASHBACK: Grandmaster; Thor; Captain America [Steve Rogers]; Goliath [Clint Barton] |
| 39 | Suddenly... The Super-Apes! | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Frank Giacoia; letters: Danny Crespi | Red Ghost; Super-Apes |
| 40 | Night of the Ape! | comic story | 22 | script: O'Neil, J. M. DeMatteis; pencils: John Romita Jr.; inks: Milgrom; colors: Wein; letters: Parker | Spider-Man [Peter Parker]; Red Ghost; Super-Apes; J. Jonah Jameson; Roger Hochberg; Mia Carerra |
| 41 | Spider-Man vs. the Punisher! | cover reprint (on interior page) | 1 | pencils: Frank Miller; inks: Klaus Janson | Frank Castle, Doctor Octopus, Otto Octavius, Peter Parker, Punisher, Spider-Man |
| 42 | Spider-Man: Threat or Menace? | comic story | 30 | script: Denny O'Neil; pencils: Klaus Janson, Frank Miller; inks: Klaus Janson; colors: Bob Sharen; letters: Jim Novak | Frank Castle, Doctor Octopus, J. Jonah Jameson, Otto Octavius, Peter Parker, Punisher, Robbie Robertson, Spider-Man, Ben Urich |
| 43 | Just How Strong Is... Spider-Man? | comic story | 3 | script: Mark Gruenwald; pencils: Mark Gruenwald, Bob Layton; inks: Bob Layton; letters: Joe Rosen | Aquarian, Bruce Banner, Clint Barton, Beast, Black Bolt, Black Goliath, Black Panther, Johnny Blaze, Blackagar Boltagon, Brian Braddock, Brunnhilde, Luke Cage, Captain America, Captain Britain |
| 44 | Peter Parker's Apartment! | character profile | 1 | script: Roger Stern; pencils: Marie Severin; inks: Terry Austin; letters: Gaspar Saladino | |
| 45 | Man-Wolf | character profile | 1 | script: Roger Stern; pencils: Keith Pollard; inks: Keith Pollard; letters: Jim Novak | John Jameson, Man-Wolf |
| 46 | The Jackal | character profile | 1 | script: Roger Stern; pencils: Greg LaRocque; inks: Frank Giacoia; letters: Jim Novak | Jackal, Miles Warren |
| 47 | The Punisher | character profile | 1 | script: Roger Stern; pencils: Greg LaRocque; inks: Frank Giacoia; letters: Jim Novak | Frank Castle, Punisher |
| 48 | Tarantula | character profile | 1 | script: Roger Stern; pencils: Greg LaRocque; inks: Frank Giacoia; letters: Jim Novak | Anton Miguel Rodriguez, Tarantula |
| 49 | Marvel Comics 20th Anniversary Calendar 1981 June Art Page | illustration | 1 | pencils: John Romita Jr.; inks: John Romita Jr.; colors: Pablo Marcos | |
| 50 | Marvel Comics 20th Anniversary Calendar 1981 February Page | illustration | 1 | script: Roger Stern | |
| 51 | Marvel Tales #130 Spider-Man Pinup | illustration | 1 | pencils: Marshall Rogers; inks: Marshall Rogers | Spider-Man [Peter Parker] |
| 52 | Marvel Tales #130 Spider-Man Pinup | illustration | 1 | pencils: Keith Pollard; inks: Rudy Nebres | Spider-Man [Peter Parker]; Doctor Strange |
| 53 | Marvel Super-Heroes Portfolio: The Amazing Spider-Man | illustration | 1 | pencils: Steve Fastner, Rich Larson; inks: Steve Fastner, Rich Larson; colors: Steve Fastner, Rich Larson | |
| 54 | The Doctor Will Kill You Now | illustration | 1 | | |
| 55 | The Lizard's Reptilian Revenge | illustration | 1 | | |
| 56 | When A Goblin Comes A' Calling | illustration | 1 | | |
| 57 | An Editorial Reply | illustration | 1 | | |
| 58 | The Amazing Spider-Man #208 Original Cover Art | illustration | 1 | pencils: John Romita Jr.; inks: Al Milgrom | |
| 59 | The Amazing Spider-Man #220 Unused Original Cover Art | illustration | 1 | pencils: Bob Layton; inks: Bob Layton | |
| 60 | The Amazing Spider-Man #221 Unused Original Cover Art | illustration | 1 | pencils: Bob Wiacek; inks: Bob Wiacek | |
| 61 | Shrapnel House Ad | illustration | 1 | pencils: Frank Miller; inks: Josef Rubinstein | |
| 62 | The Amazing Spider-Man Annual #14 Original Cover Art | illustration | 1 | pencils: Frank Miller; inks: Tom Palmer | |
| 63 | The Amazing Spider-Man Annual #14 Pages 16-17 Original Art | illustration | 2 | pencils: Frank Miller; inks: Tom Palmer | |
| 64 | The Amazing Spider-Man Annual #15 Page 18 Original Art | illustration | 1 | pencils: Frank Miller; inks: Klaus Janson | |
| 65 | The Amazing Spider-Man Annual #26 Page 18 Original Art | illustration | 1 | pencils: Frank Miller; inks: Klaus Janson | |
| 66 | The Sensational Spider-Man TPB Cover | cover reprint (on interior page) | 2 | pencils: Frank Miller | Frank Castle, Doctor Strange, Peter Parker, Punisher, Spider-Man, Stephen Strange |
| 67 | The Complete Frank Miller Spider-Man HC Cover | cover reprint (on interior page) | 2 | pencils: Frank Miller; inks: Frank Miller; colors: Tom Smith | |
| 68 | Spider-Man vs. Doctor Octopus TPB Cover | cover reprint (on interior page) | 1 | pencils: Rob Hunter; inks: Rob Hunter; colors: Steve Buccellato | |
| 69 | Epic Collection | promo (ad from the publisher) | 1 | letters: typeset | |
| 70 | A New Creative Era for Spider-Man Begins! | promo (ad from the publisher) | 1 | | |