| 0 | - | cover | 1 | pencils: Ed McGuinness; inks: Mark Farmer; colors: Marcio Menyz | Doctor Octopus, Otto Octavius, Peter Parker, Spider-Man |
| 1 | - | promo (ad from the publisher) | 1 | letters: typeset | |
| 2 | - | credits, title page | 3 | letters: typeset | |
| 3 | Free Comic Book Day: Spider-Man / Venom | cover reprint (on interior page) | 1 | pencils: Patrick Gleason; inks: Patrick Gleason; colors: Bryan Valenza | Eddie Brock, Peter Parker, Spider-Man, Venom |
| 4 | Hunting Bait | comic story | 8 | script: Zeb Wells; pencils: Patrick Gleason; inks: Patrick Gleason; colors: Marcio Menyz; letters: VC's Joe Caramagna | Doctor Octopus, Kraven the Hunter, Sergei Kravinoff, Otto Octavius, Peter Parker, Spider-Man |
| 5 | 27 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Black Cat, Doctor Octopus, Felicia Hardy, Otto Octavius, Peter Parker, Spider-Man |
| 6 | - | comic story | 19 | script: Zeb Wells; pencils: Ed McGuinness; inks: Mark Farmer; colors: Marcio Menyz; letters: VC's Joe Caramagna | Black Cat, Doctor Octopus, Felicia Hardy, J. Jonah Jameson, Dr. Ashley Kafka, Otto Octavius, Norman Osborn, Peter Parker, Queen Goblin, Herman Schultz, Shocker, Spider-Man |
| 7 | 28 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Doctor Octopus, Gold Goblin, Otto Octavius, Norman Osborn, Peter Parker, Spider-Man |
| 8 | - | comic story | 20 | script: Zeb Wells; pencils: Ed McGuinness; inks: Mark Farmer; colors: Marcio Menyz; letters: VC's Joe Caramagna | Doctor Octopus, Gold Goblin, J. Jonah Jameson, Kraven the Hunter, Sergei Kravinoff, Otto Octavius, Norman Osborn, Peter Parker, Spider-Man |
| 9 | 29 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Marcio Menyz | Peter Parker, Spider-Man |
| 10 | - | comic story | 20 | script: Zeb Wells; pencils: Ed McGuinness; inks: Mark Farmer; colors: Marcio Menyz; letters: VC's Joe Caramagna | Doctor Octopus, J. Jonah Jameson, Otto Octavius, Norman Osborn, Peter Parker, Rek-Rap, Spider-Man |
| 11 | #27 Variant | cover reprint (on interior page) | 0.25 | pencils: Lee Garbett; inks: Lee Garbett; colors: Lee Garbett | |
| 12 | #27 Pride Variant | cover reprint (on interior page) | 0.25 | pencils: Lucas Werneck; inks: Lucas Werneck; colors: Lucas Werneck | |
| 13 | #28 Variant | cover reprint (on interior page) | 0.25 | pencils: Olivier Coipel; inks: Olivier Coipel; colors: Olivier Coipel | |
| 14 | #28 Pride Variant | cover reprint (on interior page) | 0.25 | pencils: Lucas Werneck; inks: Lucas Werneck; colors: Lucas Werneck | |
| 15 | 30 | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Mark Farmer; colors: Marcio Menyz | Doctor Octopus, Otto Octavius, Peter Parker, Spider-Man |
| 16 | - | comic story | 21 | script: Zeb Wells; pencils: Ed McGuinness; inks: Mark Farmer, Cliff Rathburn, Ed McGuinness; colors: Marcio Menyz; letters: VC's Joe Caramagna | Doctor Octopus, Gold Goblin, J. Jonah Jameson, Otto Octavius, Norman Osborn, Peter Parker, Spider-Man |
| 17 | 31 | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Scott Hanna; colors: Marcio Menyz | Lonnie Lincoln, Peter Parker, Spider-Man, Tombstone |
| 18 | - | credits, title page | 1 | letters: typeset | |
| 19 | - | comic story | 38 | script: Zeb Wells; pencils: John Romita Jr., Emilio Laiso, Zé Carlos; inks: Scott Hanna, Emilio Laiso, Zé Carlos; colors: Marcio Menyz, Bryan Valenza; letters: VC's Joe Caramagna | Beetle, Black Cat, Black Mariah, Betty Brant, Elaine Coll, Crime Master, Diamondback, Mariah Dillard, Lorina Dodson, Electro, Francine Frye, Hammerhead, Felicia Hardy, Lady Octopus |
| 20 | - | credits, title page | 2 | letters: typeset | |
| 21 | - | comic story | 5 | script: Zeb Wells; pencils: David López; inks: David López; colors: KJ Diaz; letters: VC's Joe C. | Kamala Khan, Ms. Marvel, Peter Parker, Spider-Man |
| 22 | The Man with All the Answers | comic story | 3 | script: Dan Slott; pencils: Mark Bagley; inks: John Dell; colors: Edgar Delgado; letters: VC's Joe Caramagna | 8-Ball, Doctor Octopus, Norton Fester, Jeff Hagees, Looter, Otto Octavius |
| 23 | - | comic story | 7 | script: Celeste Bronfman; pencils: Alba Glez; inks: Elisabetta D'Amico, Craig Yeung; colors: Jim Campbell; letters: VC's Joe Caramagna | Felicia Hardy, Jackpot, Paul Rabin, Mary Jane Watson |
| 24 | - | comic story | 8 | script: Steve Foxe; pencils: Eric Koda; inks: Wade von Grawbadger; colors: Guru-eFX; letters: VC's Joe Caramagna | Beetle, Danielle Cage, Captain Marvel, Julia Carpenter, Carol Danvers, Lorina Dodson, Jessica Drew, Brian Hibbs, Jessica Jones, Kangaroo, Janice Lincoln, Madame Web, Tony Masters, Peter Parker |
| 25 | The Mother of Invention | comic story | 4 | script: Dan Slott; pencils: Paco Medina; inks: Paco Medina; colors: Erick Arciniega; letters: VC's Joe Caramagna | Curt Connors, Richard Deacon, Mac Gargan, Human Fly, Lizard, Morbius, Michael Morbius, Rhino, Scorpion, Aleksei Sytsevich |
| 26 | The Case of Perry Thomas: A Spidey Situation | comic story | 5 | script: Albert Monteys; pencils: Albert Monteys; inks: Albert Monteys; colors: Albert Monteys; letters: Albert Monteys | Curt Connors, Daredevil, Max Dillon, Electro, Human Torch, Lizard, Flint Marko, Matt Murdock, Peter Parker, Rhino, Sandman, Spider-Man, Johnny Storm, Aleksei Sytsevich |
| 27 | Loosey Goosey | comic story | 2 | script: Cale Atkinson; pencils: Cale Atkinson; inks: Cale Atkinson; colors: Cale Atkinson; letters: Cale Atkinson | Doctor Octopus, Otto Octavius, Peter Parker, Spider-Man |
| 28 | Huntress | comic story | 3 | script: Zeb Wells; pencils: Gleason; inks: Gleason; colors: Edgar Delgado; letters: VC's Caramagna | Dr. Ashley Kafka, Kraven the Hunter, Sergei Kravinoff, Peter Parker, Queen Goblin, Spider-Man |
| 29 | - | comic story | 5 | script: Kaare Andrews; pencils: Kaare Andrews; inks: Kaare Andrews; colors: Kaare Andrews; letters: VC's Joe Caramagna | Wilson Fisk, Mayor Waters, Peter Parker, Spider-Man, Mary Jane Watson |
| 30 | #29 Hellfire Gala Variant | cover reprint (on interior page) | 0.25 | pencils: David Nakayama; inks: David Nakayama; colors: David Nakayama | |
| 31 | #29 Variant | cover reprint (on interior page) | 0.25 | pencils: Marco Checchetto; inks: Marco Checchetto; colors: Richard Isanove | |
| 32 | #30 Variant | cover reprint (on interior page) | 0.25 | pencils: Mike Vosburg; inks: Mike Vosburg; colors: Rachelle Rosenberg | |
| 33 | #30 Variant | cover reprint (on interior page) | 0.25 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: Rachelle Rosenberg | |
| 34 | #30 Variant | cover reprint (on interior page) | 0.25 | pencils: Skottie Young; inks: Skottie Young; colors: Skottie Young | |
| 35 | #31 Women of Marvel Variant | cover reprint (on interior page) | 0.25 | pencils: Elena Casagrande; inks: Elena Casagrande; colors: Jordie Bellaire | |
| 36 | #31 Variant | cover reprint (on interior page) | 0.25 | pencils: George Pérez; inks: George Pérez; colors: Alex Sinclair | |
| 37 | #31 Variant | cover reprint (on interior page) | 0.25 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | |
| 38 | #31 Negative Space Variant | cover reprint (on interior page) | 0.25 | pencils: John Tyler Christopher; inks: John Tyler Christopher; colors: John Tyler Christopher | |
| 39 | #31 2nd Printing Variant | cover reprint (on interior page) | 0.25 | pencils: Humberto Ramos; inks: Humberto Ramos; colors: Edgar Delgado | |
| 40 | #31 2nd Printing Variant | cover reprint (on interior page) | 0.5 | pencils: Skan; inks: Skan; colors: Skan | |
| 41 | - | promo (ad from the publisher) | 1 | letters: typeset | |
| 42 | - | promo (ad from the publisher) | 1 | pencils: John Romita Jr.; inks: Scott Hanna; colors: Marcio Menyz | Lonnie Lincoln, Peter Parker, Spider-Man, Tombstone |