| 0 | It Starts Here! | cover | 1 | pencils: Steve McNiven; inks: Dexter Vines; colors: Morry Hollowell | J. Jonah Jameson, Peter Parker, Spider-Man |
| 1 | Brand New Day [Part 1] | comic story | 25 | script: Dan Slott; pencils: Steve McNiven; inks: Dexter Vines; colors: Morry Hollowell; letters: VC's Cory Petit | Betty Brant, Carlie Cooper, Alana Jobson First, Wilson Fisk, Mac Gargan, Green Goblin, Hammerhead, Lily Hollister, Jackpot First, J. Jonah Jameson, Kingpin, Martin Li, Mister Negative, Harry Osborn |
| 2 | Spider-Man: The New Status Quo! | comic story | 2 | script: Bob Gale, Marc Guggenheim, Dan Slott, Zeb Wells; pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White; letters: Virtual Calligraphy, Cory Petit | Harry Osborn, May Parker, Peter Parker, Spider-Man, Gwen Stacy, Mary Jane Watson |
| 3 | Park Avenue Interlude | comic story | 3 | script: Marc Guggenheim; pencils: Greg Land; inks: Jay Leisten; colors: Justin Ponsor; letters: VC's Cory Petit | Alana Jobson First, Lily Hollister, Jackpot First, Menace First |
| 4 | The Astonishing Aunt May! | comic story | 3 | script: Bob Gale; pencils: Phil Winslade; inks: Phil Winslade; colors: Chris Chuckry; letters: Virtual Calligraphy, Cory Petit | May Parker |
| 5 | Harry and the Hollisters | comic story | 3 | script: Zeb Wells; pencils: Mike Deodato; inks: Mike Deodato; colors: Rain Beredo; letters: VC's Cory Petit | Bill Hollister First, Lily Hollister, Harry Osborn |
| 6 | A Message from Your Brand New Editor | text article | 1 | script: Steve Wacker; pencils: Steve McNiven; inks: Dexter Vines; colors: Morry Hollowell | |