| 0 | - | cover | 1 | pencils: Carlos Valenzuela; inks: Carlos Valenzuela; colors: Carlos Valenzuela | Dana Scully; Fox Mulder; Bing Ellinson; Millie Ohio [Humility Ohio]; Mr. Xero |
| 1 | Previously on The X-Files... | recap | 1 | pencils: Carlos Valenzuela, Robert Hack, Francesco Francavilla; inks: Carlos Valenzuela, Robert Hack, Francesco Francavilla; colors: Carlos Valenzuela, Stephen Downer, Francesco Francavilla | Dana Scully; Fox Mulder; Bing Ellinson; Millie Ohio [Humility Ohio] |
| 2 | - | comic story | 20 | script: Karl Kesel; pencils: Greg Scott, Vic Malhotra; inks: Greg Scott, Vic Malhotra; colors: Mat Lopes; letters: Robbie Robbins | Dana Scully; Fox Mulder; Bing Ellinson; Dr. Dell Spoon; Dr. Yates; Dorothy Spears; Millie Ohio [Humility Ohio]; Ollie; Mr. Xero |
| 3 | - | promo (ad from the publisher) | 1 | pencils: Carlos Valenzuela; inks: Carlos Valenzuela; colors: Carlos Valenzuela | Dana Scully; Fox Mulder; Bing Ellinson; Millie Ohio [Humility Ohio] |
| 4 | Cosmic Craziness! | in-house column | 2 | script: Dirk Wood | |
| 5 | - | promo (ad from the publisher) | 1 | letters: typeset | Beverly Crusher; Julian Bashir; Katherine Pulaski; Leonard McCoy |
| 6 | - | promo (ad from the publisher) | 1 | letters: typeset | Dana Scully; Fox Mulder |
| 7 | Squidder | promo (ad from the publisher) | 1 | pencils: Ben Templesmith; inks: Ben Templesmith; colors: Ben Templesmith | Squidder |
| 8 | - | promo (ad from the publisher) | 1 | pencils: Walter Simonson; inks: Walter Simonson; colors: Laura Martin | Thor |
| 9 | Borderlands | promo (ad from the publisher) | 1 | pencils: Agustín Padilla; inks: José Avilés; colors: Esther Sanz; letters: Tom Waltz | |
| 11 | Trust No One. | promo (ad from the publisher) | 1 | letters: typeset | |