| 0 | - | cover | 1 | pencils: Mark Frederickson; inks: Mark Frederickson; colors: Mark Frederickson | |
| 1 | Special Jackpot Issue | table of contents | 2 | pencils: Kelly Freas; inks: Kelly Freas; colors: Kelly Freas | |
| 2 | A Mad Look at Las Vegas | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; letters: Sergio Aragonés | |
| 3 | Late One Night at the Roulette Table | comic story | 1 | script: Duck Edwing; pencils: Don Martin; inks: Don Martin | |
| 4 | Mad Investigates the Sordid Business of Gambling | comic story | 6 | script: Al Jaffee; pencils: Wallace Wood; inks: Wallace Wood | C. C. Clavendish III; Lotta Rees; Sam Grafter; Dr. Sidney A. Kindlyfellow |
| 5 | When Casino Gambling Comes to Your City | comic story | 2 | script: Stan Hart; pencils: George Woodbridge; inks: George Woodbridge | |
| 6 | Sure Bets in Vegas | comic story | 2 | script: Scott Maiko | |
| 7 | The Sights and Sounds of the U.S.A. | comic story | 2 | script: Larry Siegel, Frank Jacobs; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 8 | Mad's Gambler of the Year | comic story | 5 | script: Mike Snider; pencils: George Woodbridge, Robert Dale, Phil Franke; inks: George Woodbridge, Robert Dale, Phil Franke | I-Wanna Chump; Ace Tropicana |
| 9 | In a Las Vegas Hotel Lobby | comic story | 1 | script: Don Edwing; pencils: George Woodbridge; inks: George Woodbridge | |
| 10 | Las Vegas Spy Vs Spy | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper; colors: Peter Kuper; letters: Peter Kuper | |
| 11 | Mad's Guide to Proper All-You-Can-Eat Buffet Etiquette | comic story | 2 | script: Dick DeBartolo; pencils: Tom Bunk; inks: Tom Bunk; colors: Tom Bunk | |
| 12 | Heartbreaking Problems of Aging Elvis Impersonators | comic story | 2 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell; colors: John Caldwell; letters: John Caldwell | |
| 13 | You're a Winner and a Loser | comic story | 3 | script: Desmond Devlin; pencils: Tom Bunk; inks: Tom Bunk | |
| 14 | Early One Evening in Atlantic City | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin; letters: Don Martin | |
| 15 | Life a Game of Chance! | comic story | 2 | script: Tammy Golden; pencils: Tom Richmond; inks: Tom Richmond; colors: Tom Richmond | |
| 16 | Thanks to the Popularity of Poker... | comic story | 3 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell; letters: John Caldwell | |
| 17 | Early One Evening in Las Vegas | comic story | 1 | script: Don Edwing; pencils: Don Martin; inks: Don Martin | |
| 18 | A Mad Peek Behind the Scenes at Celebrity Poker Showdown | comic story | 3 | script: Desmond Devlin, John Caldwell, David Shayne; pencils: Tom Richmond; inks: Tom Richmond; colors: Tom Richmond | |
| 19 | Ben Affleck the Art of the Poker Face | comic story | 1 | script: Andrew J. Schwartzberg; pencils: Drew Friedman; inks: Drew Friedman | |
| 20 | Choose Your Fantasy Football League Carefully! | comic story | 2 | script: Matt Cohen; pencils: Hermann Mejía; inks: Hermann Mejía; colors: Hermann Mejía | |
| 21 | Sure Bets in Sports | comic story | 3 | script: Tom Koch; pencils: Jack Davis; inks: Jack Davis | |
| 22 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías; colors: Carrie Strachan | The Black Spy; The White Spy |
| 23 | Other Betting Pools | comic story | 2 | script: Lou Silverstone; pencils: George Woodbridge; inks: George Woodbridge | |
| 24 | Pigeon Drop | comic story | 2 | script: Jon Adams; pencils: Jon Adams; inks: Jon Adams; colors: Jon Adams | |
| 25 | Mad's Celebrity Cause-Of-Death Betting Odds | comic story | 1 | script: Mike Snider; pencils: Hermann Mejía; inks: Hermann Mejía | Johnny Knoxville |
| 26 | What New Game of Chance Has People Rolling the Dice on Streets All Over? | activity | 1 | script: Johnny Sampson; pencils: Johnny Sampson; inks: Johnny Sampson; colors: Johnny Sampson | |
| 27 | Jack Squat App | photo story | 1 | script: Desmond Devlin; pencils: Mike Loew; inks: Mike Loew; colors: Mike Loew | |