| 0 | You'll Go "Ape" Over This Issue of Mad | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | Be Suspicious | illustration | 1 | pencils: Lester Krauss; inks: Lester Krauss | |
| 2 | Mad's Valentines to American Industry | comic story | 2 | script: Frank Jacobs; pencils: Mort Drucker, Don Martin, Jack Rickard, Bob Clarke, George Woodbridge, Paul Coker Jr.; inks: Mort Drucker, Don Martin, Jack Rickard, Bob Clarke, George Woodbridge, Paul Coker Jr. | |
| 3 | The Prophet | cartoon | 1 | pencils: Joe Orlando; inks: Joe Orlando | |
| 4 | 007 | comic story | 6 | script: Frank Jacobs; pencils: Mort Drucker; inks: Mort Drucker | Sean Connery [as James Bomb]; Bernard Lee [as M]; Lois Maxwell [as Miss Moneypenney]; Tasti Delight; Mickey Spillane [as Mike Hammer]; The Beatles [John Lennon; Paul McCartney; George Harrison; Ringo Starr]; Audrey Hepburn; Richard Burton; Hayley Mills; Winston Churchill; Rex Harrison; Peter Sellers |
| 5 | Famous People's Home-Study Courses | comic story | 4 | script: Al Jaffee; pencils: Bob Clarke; inks: Bob Clarke | |
| 6 | A Fine Day in the City | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 7 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 8 | A Mad Look at Winter Sports | cartoon | 2 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 9 | Specific "Form Answer Letters" | comic story | 3 | script: Arnie Kogen | |
| 10 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 11 | The Sights and Sounds of the U.S.A.: Ft. Worth, Texas | comic story | 2 | script: Larry Siegel, Frank Jacobs; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 12 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 13 | Neurotic Magazine | comic story | 6 | script: Stan Hart; pencils: George Woodbridge; inks: George Woodbridge | |
| 14 | The Spectator | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 15 | Basketball Foto-Plays | photo story | 1 | script: Arnie Kogen; pencils: UPI, AP/Wide World; inks: UPI, AP/Wide World | |
| 16 | The Lighter Side of Kids' Parties | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 17 | TV Commercials | comic story | 2 | script: Stan Hart; pencils: Jack Rickard; inks: Jack Rickard | |
| 18 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy; The Gray Spy |
| 19 | Son of Mighty Joe Kong | comic story | 6 | script: Dick DeBartolo; pencils: Mort Drucker; inks: Mort Drucker | James Garner [as Robert Headstrong]; Doris Day [as Rae Faye]; Dick Van Dyke [as Bruce Cabbage] |
| 20 | Which National Symbol is Going to Need the Biggest Repair Job? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 21 | After the Most Hair-Raising Adventure of My Life | illustration | 1 | pencils: Lester Krauss, Bob Clarke; inks: Lester Krauss, Bob Clarke; colors: Lester Krauss, Bob Clarke | |