| 0 | Mad Congratulates Richard Nixon | cover | 1 | pencils: Bob Clarke; inks: Bob Clarke; colors: Bob Clarke | Alfred E. Neuman, Richard Nixon |
| 1 | The Furd Foulcar | cartoon | 1 | pencils: Bob Clarke; inks: Bob Clarke | Charlie Brown, Lucy Van Pelt |
| 2 | Vital Features | table of contents | 2 | pencils: various; inks: various; letters: typeset | |
| 3 | - | letters page | 1.45 | letters: typeset | |
| 4 | Ring out the Old Year and Ring in the New! | promo (ad from the publisher) | 0.55 | pencils: Mort Drucker; inks: Mort Drucker | Santa Claus |
| 5 | The Producer and I | comic story | 6 | pencils: Mort Drucker; inks: Mort Drucker | Charlie Chaplin, Burt Lancaster First, Frank Sinatra |
| 6 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy First, The White Spy First |
| 7 | Tee Vee U. | comic story | 4 | script: Sy Reit; pencils: Bob Clarke; inks: Bob Clarke | John Daly; Dorothy Killgallen; Bill Cullen; Ralph Edwards; President Ulysses Simpson Grant |
| 8 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy First, The White Spy First |
| 9 | The European Tourist's Guide to the United States | comic story | 7 | script: Frank Jacobs; pencils: Joe Orlando; inks: Joe Orlando | |
| 10 | A Mad Peek Behind the Scenes | comic story | 2 | script: Phil Hahn; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | Dr. Benjamin Spock |
| 11 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy First, The White Spy First |
| 12 | The Mad Shakespeare Primer | comic story | 3 | script: Phil Hahn; pencils: Wally Wood; inks: Wally Wood | Julius Caesar, Juliet Capulet, Romeo Montague |
| 13 | Mad's College Songs and Cheers for Traitors, Defeatists and Cowards | comic story | 3 | script: Larry Siegel; pencils: George Woodbridge; inks: George Woodbridge | |
| 14 | Dieting | comic story | 3 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 15 | "Warm-Ups" to Everything | comic story | 4 | script: Gary Belkin; pencils: George Woodbridge; inks: George Woodbridge | |
| 16 | Educational Toys | comic story | 3 | script: Al Jaffee; pencils: Bob Clarke; inks: Bob Clarke | |
| 17 | 20 Years in the Shipping Dept. | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 18 | Naked Town | comic story | 4 | script: Larry Siegel; pencils: Mort Drucker; inks: Mort Drucker | Horace McMahon [as Lt. Poker]; Paul Burke [as Det. Flinch]; Lt. Mascara |
| 19 | For Mad Christmas Gift-Giving this Year...Have a Ball! | promo (ad from the publisher) | 1 | pencils: ? (photo); inks: ? (photo); letters: typeset | |
| 20 | Mad Congratulates John Kennedy | cover | 1 | pencils: Bob Clarke; inks: Bob Clarke; colors: Bob Clarke | Alfred E. Neuman, John F. Kennedy |
| 21 | Appropriate Casting for Old Movies | text article | 0 | letters: typeset | |