| 0 | The 20 Dumbest People, Events and Things 2017 | cover | 1 | pencils: Mark Fredrickson; inks: Mark Fredrickson; colors: Mark Fredrickson | Alfred E. Neuman; President Donald Trump |
| 1 | Go MAD for the Holidays! | promo (ad from the publisher) | 1 | letters: typeset | |
| 2 | - | table of contents | 1 | pencils: various; inks: various; colors: various; letters: typeset | |
| 3 | - | letters page | 2.5 | pencils: various; inks: various; colors: various; letters: typeset | |
| 4 | - | statement of ownership | 0.25 | letters: typeset | |
| 5 | - | credits, title page | 0.25 | letters: typeset | |
| 6 | Have a Fabulous, Wonderful, Great Day! | promo (ad from the publisher) | 1 | letters: typeset | |
| 7 | The Fundalini Pages | comic story | 3 | script: Jeff Kruse, Matt Lassen, Peter Kuper, Brian Boone, Mike Morse, Kenny Keil; pencils: Bob Staake, Peter Kuper, Chris Houghton, John Kerschbaum, John McNamee, Rick Tulka; inks: Bob Staake, Peter Kuper, Chris Houghton, John Kerschbaum, John McNamee, Rick Tulka | |
| 8 | 20 Dumbest | cartoon | 1 | script: Mike Morse; pencils: Scott Bricher; inks: Scott Bricher | |
| 9 | 1 Team Trump Colludes with Russians | cartoon | 1 | script: Mike Morse; pencils: Mark Fredrickson; inks: Mark Fredrickson | President Donald Trump |
| 10 | 2 Bill O'Reilly the Trouble with the Perv, Part 1 | cartoon | 1 | script: Mike Morse | Bill O'Reilly |
| 11 | 3 United Airlines' Passenger Removal | text story | 1 | script: Joe Raiola; pencils: Charlie Kadau; inks: Charlie Kadau | |
| 12 | 4 White Supremacists March the Bigot Losers | cartoon | 1 | script: Mike Morse; pencils: Tom Richmond; inks: Tom Richmond; colors: Tom Richmond | |
| 13 | 5 Academy Award Show Screw-Up Oscar Mired | cartoon | 1 | pencils: Chris Wahl; inks: Chris Wahl | |
| 14 | 6 Trump on Twitter Antisocial Media | cartoon | 1 | pencils: Mike Loew; inks: Mike Loew | President Donald Trump |
| 15 | 7 Sean Spicer, White House Press Secretary Spinner and Loser | cartoon | 1 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | Sean Spicer |
| 16 | 8 Trump vs. Kim Jong-Un Atom & Eve of Destruction | cartoon | 1 | pencils: Tom Richmond; inks: Tom Richmond | President Donald Trump; Kim Jong-Un |
| 17 | 9 Mike Pence Won't Dine Alone With a Woman and Eat Us Not Into Temptation | cartoon | 1 | script: Jeff Kruse; pencils: Robert Sikoryak; inks: Robert Sikoryak | |
| 18 | 10 Trump Bans Transgender Soldiers F.U. For Your Service | cartoon | 1 | pencils: Richard Williams; inks: Richard Williams | President Donald Trump |
| 19 | 11 Trump's Muslim Travel Ban Make America Hate Again | cartoon | 1 | script: Charlie Kadau; pencils: Liz Lomax | |
| 20 | 12 Harvey Weinstein Trouble with the Perv, Part 2 | cartoon | 1 | pencils: Drew Friedman; inks: Drew Friedman | |
| 21 | 13 Chris Christie Closes Jersey Beaches Thar He Blows! | cartoon | 1 | pencils: Roberto Parada; inks: Roberto Parada | |
| 22 | 14 Bill and Kathy's Tasteless Jokes from Jest to Worst | cartoon | 1 | letters: typeset | |
| 23 | 15 Alex Jones Fringe Watching | cartoon | 1 | pencils: Mark Stutzman; inks: Mark Stutzman | |
| 24 | 16 Kyrie Irving Says the Earth Is Flat Sphere and Loathing | cartoon | 1 | pencils: Anton Emdin; inks: Anton Emdin | |
| 25 | 17 White House Staff Firings S#!t, Canned | cartoon | 1 | pencils: Dean MacAdam; inks: Dean MacAdam | |
| 26 | 18 What Widespread Addiction In America Is Whirling Out of Control? | cartoon | 1 | pencils: Al Jaffee; inks: Al Jaffee | |
| 27 | 19 NFL Blackballs Kaepernick Personnel Foul | comic story | 2 | script: Desmond Devlin; pencils: Ward Sutton; inks: Ward Sutton | Colin Kaepernick; Roger Goddell; President Donald Trump; Jerry Jones |
| 28 | 20 Trump's Response to Puerto Rico Throwing In the Towel | comic story | 1 | pencils: Alejandro Rivas; inks: Alejandro Rivas | President Donald Trump |
| 29 | Dewey Derwin Destroys the World! | comic story | 4 | script: Kenny Keil; pencils: Justin Peterson; inks: Justin Peterson | |
| 30 | Clodco Wholesale | comic story | 1 | script: Jeff Kruse; pencils: Mike Loew; inks: Mike Loew | |
| 31 | Projectile Vomit Baby Through History | comic story | 2 | script: Scott Nickel; pencils: Scott Nickel; inks: Scott Nickel; letters: Scott Nickel | |
| 32 | Tinder Bio Translations | comic story | 2 | script: Kenny Keil; pencils: Stephen Silver; inks: Stephen Silver | |
| 33 | Complete Your Mad Library | promo (ad from the publisher) | 2 | letters: typeset | |
| 34 | - | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | |
| 35 | Why We Get the Holiday Blahs | comic story | 3 | script: Barry Liebmann | |
| 36 | Plane Bull$#*t! | comic story | 0.5 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | |
| 37 | WTF Jeff? or My Roommate Might Be a Serial Killer | comic story | 0.5 | script: Kit Lively; pencils: Scott Nickel; inks: Scott Nickel | |
| 38 | Almost Perfect Universe | comic story | 0.25 | script: Dakota McFadzean; pencils: Dakota McFadzean; inks: Dakota McFadzean; letters: Dakota McFadzean | |
| 39 | Game of Bones | comic story | 0.25 | script: Feggo; pencils: Feggo; inks: Feggo | |
| 40 | It Only Hurts When I Laugh | comic story | 0.5 | script: Christopher Baldwin; pencils: Christopher Baldwin; inks: Christopher Baldwin; letters: Christopher Baldwin | |
| 41 | Jet Wingman | comic story | 1 | script: Eric Haven; pencils: Eric Haven; inks: Eric Haven; letters: Eric Haven | |
| 42 | 10 Toons by Teresa Burns Parkhurst | comic story | 2 | script: Teresa Burns Parkhurst; pencils: Teresa Burns Parkhurst; inks: Teresa Burns Parkhurst; letters: Teresa Burns Parkhurst | |
| 43 | A Mad Look at Food Trucks | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Tom Luth | |
| 44 | The Gap-Toothed Gallery | illustration | 1 | pencils: Michael DeForge; inks: Michael DeForge; colors: Michael DeForge | |
| 45 | Our Best Material on America's Greatest* President | promo (ad from the publisher) | 1 | letters: typeset | |
| 46 | Important Bike Safety Tips! | comic story | 1 | script: Dick DeBartolo; pencils: John Martz; inks: John Martz | |