| 0 | Glee | cover | 1 | pencils: Mark Fredrickson; inks: Mark Fredrickson; colors: Mark Fredrickson | Alfred E. Neuman; Sue Sylvester; Will Schuester; Rachel Berry |
| 1 | Haunted By The Ghost of Christmas Presents? | promo (ad from the publisher) | 1 | pencils: George Woodbridge; inks: George Woodbridge | Alfred E. Neuman (as Jacob Marley); Ebenezer Scrooge |
| 2 | Departments | table of contents | 1 | pencils: various; inks: various; letters: typeset | Alfred E. Neuman; Smokey Bear; George W. Bush; Black Spy; White Spy; Shrew Stillfester |
| 3 | Random Samplings of Reader Mail | letters page | 2.75 | script: John Ficarra | Sergio Aragones; Alfred E. Neuman; Joe Masterman; Andrew Spitzer; Christina Vanko; Jon Hamm; Matthew Weiner; John Slattery; Vincent Kartheiser; Bryan Batt; Kent Smith |
| 5 | An Offer You Can't De-Fuse! | promo (ad from the publisher) | 0.5 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | Black Spy; White Spy |
| 6 | - | credits, title page | 0.25 | letters: typeset | |
| 7 | The Fundalini Pages | comic story | 6 | script: Jeff Kruse, Glen LeLievre, Jacob Lambert, Dave Croatto, Todd Clark, Scott Nickel; pencils: Mort Drucker, Glen LeLievre, Evan Dorkin, Bob Staake, Rick Tulka, Todd Clark; inks: Mort Drucker, Glen LeLievre, Sarah Dyer, Bob Staake, Rick Tulka, Todd Clark; colors: istockphoto.com / Deejpilot | Michael Steele; Jesus Christ; Smokey Bear; Lindsay Lohan; Mrs. Lohan; Lebron James; Glenn Beck; Lady Gaga; Lyndsy Fonseca; David Henrie; Levi Johnston; Cathy; Irving; Cathy's mother; Cathy's father |
| 9 | An Explosive Collection of Classic Spy Vs. Spy | promo (ad from the publisher) | 1 | pencils: Peter Kuper; inks: Peter Kuper | |
| 10 | Glee-Tarded | comic story | 5 | script: Arnie Kogen; pencils: Tom Richmond; inks: Tom Richmond | Mr. Schmoo; Rugaluch; Epiphany; Cluck; Shrew Stillfester; Justin Beiber (cameo); Principal Friggens; Simon Cowell; Randy Jackson; Dim; Tuna; Archie Andrews (cameo); Betty Cooper (cameo); Veronica Lodge (cameo); Jughead Jones (cameo); Lady Gaga (statue) |
| 11 | A MAD Look At The Oil Spill | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Tom Luth | Aquaman |
| 12 | The Fastest Way To Learn A Language | comic story | 1 | pencils: Robert Kenny, Retna Ltd., Corbis; inks: Robert Kenny, Retna Ltd., Corbis; colors: Robert Kenny, Retna Ltd., Corbis | Mel Gibson |
| 13 | A Beginner's Guide To A More Prosperous Career In Panhandling | comic story | 2 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell; letters: John Caldwell | |
| 14 | Some Serious Monkey Business | text story | 2 | script: Brian McConnachie; pencils: Leonard Rodriguez; inks: Leonard Rodriguez; colors: Leonard Rodriguez | Dr. Barry Coleman; Mr. Aims; Dr. Charmers |
| 15 | Tea Party Logic | comic story | 2 | script: Barry Liebmann; pencils: Paul Coker; inks: Paul Coker | Sarah Palin |
| 16 | Signs You've Got A Bad Roommate | comic story | 2 | script: Teresa Burns Parkhurst; pencils: Teresa Burns Parkhurst; inks: Teresa Burns Parkhurst; letters: Teresa Burns Parkhurst | |
| 17 | The MAD World of...Fashion | comic story | 3 | script: Stan Sinberg; pencils: Marc Hempel; inks: Marc Hempel | |
| 18 | On Sale Now Wherever Books Are Still Sold! | promo (ad from the publisher) | 1 | pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 19 | Deleted Passages From George W. Bush's New Book | text article | 2 | script: Charlie Kadau; pencils: Sam Viviano; inks: Sam Viviano | George W. Bush |
| 20 | MAD's Less-Than-Magical Outtakes From Harry Potter And The Deathly Hallows | comic story | 2 | pencils: ? (photo); inks: ? (photo); colors: ? (photo); letters: typeset | Harry Potter; Ron Weasley; Hermione Granger; Lord Voldemort |
| 21 | Spy Vs. Spy | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | Black Spy; White Spy |
| 22 | The 2010 Lack-Of-Entertainment Book | comic story | 2 | script: Scott Maiko | |
| 23 | Subscribe To MAD And Own A Piece of MAD History! | promo (ad from the publisher) | 1 | pencils: Norman Mingo; inks: Norman Mingo | Alfred E. Neuman |
| 24 | The Strip Club | comic story | 4 | script: John Kovaleski, Keith Knight, Jacob Lambert, Jason Yungbluth, Christopher Baldwin, Douglas Paszkiewicz; pencils: John Kovaleski, Keith Knight, Jacob Lambert, Jason Yungbluth, Christopher Baldwin, Douglas Paszkiewicz; inks: John Kovaleski, Keith Knight, Jacob Lambert, Jason Yungbluth, Christopher Baldwin, Douglas Paszkiewicz; letters: John Kovaleski, Keith Knight, Jacob Lambert, Jason Yungbluth, Christopher Baldwin, Douglas Paszkiewicz | Father O'Flannity; Choirboy Timmy; Lady Gaga; Doomatarians |
| 25 | MAD's Handy Quick Primer To World of Warcraft | comic story | 4 | script: Desmond Devlin; pencils: Hermann Mejía; inks: Hermann Mejía | |
| 26 | The MAD Vault 1978 | comic story | 3 | script: Al Jaffee, Frank Jacobs, Arnie Kogen, Larry Siegel, Dick DeBartolo, Stan Hart; pencils: Jack Davis, Jack Rickard, Mort Drucker, Harry North, Paul Coker, Bob Clarke; inks: Jack Davis, Jack Rickard, Mort Drucker, Harry North, Paul Coker, Bob Clarke | Nancy; Sluggo; Olivia Newton-John; John Travolta; Alfred E. Neuman; Princess Laidup; Bar-Stool; George Lucas; Jimmy Carter |
| 27 | Dead Lobster | comic story | 1 | script: Andy Ross; pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |
| 28 | What American Enterprise Is Still Widely Regarded As Too Big To Fail? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | Kim Kardashian |
| 29 | Drawn Out Dramas | filler | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | White Spy; a pope; Mickey Mouse; Donald Duck |