| 0 | Warning! One Man's Magazine May Be Another Man's Poison | cover | 1 | pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |
| 1 | Snow Job | comic story | 1 | script: Sergio Aragonés; pencils: Jack Rickard; inks: Jack Rickard; colors: Jack Rickard | |
| 2 | - | letters page | 0.67 | script: Nick Meglin; pencils: Charles Schulz; inks: Charles Schulz | |
| 3 | - | statement of ownership | 0.2 | script: William M. Gaines | |
| 4 | Why Not Have the Next Issue Sent Directly to Your Home? | promo (ad from the publisher) | 0.5 | pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 5 | 201 Minutes of a Space Idiocy | comic story | 7 | script: Dick DeBartolo; pencils: Mort Drucker; inks: Mort Drucker | Fred Flintstone (cameo); Keir Dullea [as Bowtie]; Gary Lockwood [as Poop]; William Sylvester [as Dr. Haywire]; Leonard Rossiter [as Dr. Smyles] |
| 6 | Don Martin on the Golf Course | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 7 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 8 | A Portfolio of Mad Portraits | photo story | 3 | script: Max Brandel; pencils: Max Brandel; inks: Max Brandel | John Lindsey; Liberace; Hugh Hefner; Ronald Reagan; Charles DeGaulle; Gamel Abdul Nasser; Eugene McCarthy; Pablo Picasso; Timothy Leary; J. Edgar Hoover; Twiggy; Richard Nixon |
| 9 | Spy vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 10 | The Lighter Side of Teenage Dances | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 11 | Spy vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 12 | Tiny Tim's Wallet | comic story | 2 | script: Earle Doud | |
| 13 | A Mad Look at Sex Education in the Schools | comic story | 3 | script: Jack Kent; pencils: Jack Kent; inks: Jack Kent | |
| 14 | Mad's Book Publisher of the Year | comic story | 4 | script: Stan Hart; pencils: Jack Rickard; inks: Jack Rickard | |
| 15 | The Mad Ice Hockey Primer | comic story | 3 | script: Larry Siegel; pencils: Jack Davis; inks: Jack Davis | |
| 16 | Me and My Big Mouth 2 | comic story | 2 | script: Dean Norman; pencils: Al Jaffee; inks: Al Jaffee | |
| 17 | The Mad Poetry Round Robin | comic story | 4 | script: Frank Jacobs; pencils: George Woodbridge; inks: George Woodbridge | |
| 18 | You Know You've Really Made It When... | comic story | 2 | script: Frank Ridgeway; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 19 | If Comic Characters Were Psychoanalyzed | comic story | 4 | script: Frank Jacobs; pencils: Bob Clarke; inks: Bob Clarke; letters: Bob Clarke | Charlie Brown; Snoopy; Dagwood Bumstead; Blondie Bumstead; Alexander Bumstead; Cookie Bumstead; Mr. Dithers; Donald Duck; Beetle Bailey; Sgt. Snorkel; Mary Worth |
| 20 | In the Hall of Fame | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 21 | What Is the One Thing Protest Marches Have Greatly Improved? | cartoon | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 22 | Cemetery Fillers Cigarettes | illustration | 1 | pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |