| 0 | - | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | The Mad Hate Book | comic story | 4 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 2 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 3 | Ads We'd Like to See | photo story | 2 | pencils: ? (photo); inks: ? (photo); letters: typeset | |
| 4 | One Day in a Hospital | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 5 | Songs of Food | comic story | 3 | script: Frank Jacobs; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 6 | The Life of Your Run | comic story | 6 | script: Dick DeBartolo; pencils: Mort Drucker; inks: Mort Drucker | Ben Gazzara [as Pall Dyin] |
| 7 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 8 | A Portfolio of Mad Zoo-Lulus | comic story | 2 | script: Max Brandel; pencils: Max Brandel; inks: Max Brandel | |
| 9 | What is a Born Loser? | text story | 2 | script: Tom Koch; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 10 | The Lighter Side of Camera-Bugs | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 11 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 12 | The Television Network President of the Year | comic story | 5 | script: Stan Hart; pencils: Joe Orlando; inks: Joe Orlando | Truman Capote [as Trueblood Capote]; Herman Avarice |
| 13 | Meet Ziraldo | cartoon | 2 | script: Ziraldo; pencils: Ziraldo; inks: Ziraldo | |
| 14 | Yellow Pages for Super-Heroes | comic story | 2 | script: Don Reilly; pencils: John Putnam; inks: John Putnam | |
| 15 | Winter Sports Foto-Plays | photo story | 2 | script: Arnie Kogen | |
| 16 | A Quick Stroll | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 17 | Fantastecch Voyage | comic story | 6 | script: Larry Siegel; pencils: Mort Drucker; inks: Mort Drucker | Stephen Boyd [as Steve Grunt]; Raquel Welch [as Carrie VaVoom]; Donald Pleasence [as Dr. Micro]; Arthur Kennedy [as Dr. NoCal]; Sidney Omens; Edmund O'Brien [as Mr. Conman]; Arthur O'Connell [as Donald Ream]; Irving J. Sinusitis |
| 18 | What Is Replacing Girls In Young Men's Minds? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 19 | P.H.I.L.C.O. Warns: Color TV Can Often Look This Bad! | photo story | 1 | pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |