| 0 | Special "June Groom" Issue | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | Advertising Campaigns with Ulterior Motives | comic story | 4 | script: Frank Jacobs; pencils: Jack Rickard; inks: Jack Rickard | |
| 2 | Another Mad Peek Through the Microscope | comic story | 2 | script: Phil Hahn; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 3 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 4 | Future Wit & Wisdom Books | comic story | 3 | script: Phil Hahn, Jack Hanrahan; pencils: Mort Drucker; inks: Mort Drucker | |
| 5 | In the Hospital | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 6 | Mixing Personal Politics with Careers | comic story | 3 | script: Frank Jacobs; pencils: George Woodbridge; inks: George Woodbridge | |
| 7 | Stereotype-Casting | comic story | 3 | script: Frank Jacobs; pencils: Bob Clarke; inks: Bob Clarke | |
| 8 | Mad Visits the American Mediocrity Academy | comic story | 4 | script: Larry Siegel; pencils: Jack Rickard; inks: Jack Rickard | |
| 9 | Later on in the Hospital | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 10 | A Portfolio of Shapely Mad Verse | text story | 2 | script: William Garvin | |
| 11 | The Lighter Side of High School | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 12 | Road Signs We'd Really Like to See | comic story | 2 | script: Phil Hahn, Jack Hanrahan; pencils: Bob Clarke; inks: Bob Clarke | |
| 13 | Postage Stamp Advertising | comic story | 3 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 14 | Mad Looks at the Voice Typewriter | comic story | 3 | script: Stan Hart; pencils: Bob Clarke; inks: Bob Clarke | |
| 15 | Track and Field Foto-Plays | comic story | 2 | script: Arnie Kogen | |
| 16 | Still Later in the Hospital | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 17 | Loused Up in Space | comic story | 6 | script: Dick DeBartolo; pencils: Mort Drucker; inks: Mort Drucker | Guy Williams [as John Boobinson]; June Lockhart [as Mauronne Boobinson]; Marta Kristen [as Suet Boobinson]; Angela Cartwright [as Punny Boobinson]; Billy Mumy [as Will Boobinson]; Mark Goddard [as Donce]; Jonathan Harris [as The Professor]; The Robot; David Janssen [as Dr. Richard Kimble] |
| 18 | The Kind of Fireworks Some People Would Like to See | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 19 | The Day a Gentleman Finally Offered a Lady a Tiparillo | photo story | 1 | pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |