| 0 | - | cover | 1 | pencils: Curt Swan; inks: Stan Kaye; colors: Rick Taylor; letters: Todd Klein | Jor-El, Kara Zor-El, Clark Kent, Clark Kent, Krypto, Lois Lane, Lana Lang, Lori Lemaris, Jimmy Olsen, Superbaby, Superboy, Supergirl, Superman, Perry White |
| 1 | Every Comic Book Is Someone's First Comic Book | text article | 1 | script: Mike Carlin | |
| 2 | Table of Contents | table of contents | 1 | letters: typeset | |
| 3 | Superman's First Exploit | comic story | 8 | script: Edmond Hamilton; pencils: Wayne Boring; inks: Stan Kaye; colors: Rick Taylor | |
| 4 | The Witch of Metropolis | comic story | 8 | script: Otto Binder; pencils: Kurt Schaffenberger; inks: Kurt Schaffenberger; colors: Rick Taylor | Superman [Clark Kent]; Lois Lane; Perry White |
| 5 | The Supergirl from Krypton! | comic story | 7.67 | script: Otto Binder; pencils: Al Plastino; inks: Al Plastino; colors: Rick Taylor; editing: Mort Weisinger | Superman [Kal-El; Clark Kent]; Supergirl [Kara Zor-El] (introduction, first appearance, origin); Zor-El (introduction); Miss Hart (introduction) |
| 6 | Flag of Krypton | comic story | 0.33 | colors: Rick Taylor | Krypton Flag |
| 7 | A Visit from Superman's Pal | comic story | 8 | script: Otto Binder; pencils: Curt Swan; inks: Ray Burnley; colors: Rick Taylor | Superboy; Jimmy Olsen |
| 8 | The Girl in Superman's Past! | comic story | 9.67 | script: Bill Finger; pencils: Wayne Boring; inks: Stan Kaye; colors: Rick Taylor | Superman [Clark Kent]; Lori Lemaris (introduction, first appearance); Lois Lane |
| 9 | Map of Krypton | illustration | 2 | script: Jerry Siegel; pencils: Al Plastino; inks: Al Plastino; colors: Rick Taylor | Jor-El; Lara; Kal-El |
| 10 | Coming... in the Next Giant Superman Annual | promo (ad from the publisher) | 0.33 | | |
| 11 | The Execution of Krypto | comic story | 8 | script: Otto Binder; pencils: George Papp; inks: George Papp; colors: Rick Taylor | Superboy [Clark Kent]; Krypto |
| 12 | The Fattest Girl in Metropolis | comic story | 7.67 | script: Otto Binder; pencils: Kurt Schaffenberger; inks: Kurt Schaffenberger; colors: Rick Taylor | Lois Lane; Superman; Professor Colby; Perry White; Jimmy Olsen |
| 13 | Coming... Super-Attractions! | promo (ad from the publisher) | 0.33 | | |
| 14 | The Super-Brain of Jimmy Olsen | comic story | 8 | script: Otto Binder; pencils: Curt Swan; inks: Ray Burnley; colors: Rick Taylor | Jimmy Olsen; Lois Lane; Superman; Perry White; Professor Potter (first appearance) |
| 15 | The Super-Key to Fort Superman | comic story | 12 | script: Jerry Coleman; pencils: Wayne Boring; inks: Stan Kaye; colors: Rick Taylor | Superman; Lois Lane; Jimmy Olsen; Batman; Joker (image on trophy) |
| 16 | - | promo (ad from the publisher) | 1 | script: Alvin Schwartz; pencils: Win Mortimer; inks: Win Mortimer | |
| 17 | Famous First Issues! [Superman #1] | cover reprint (on interior page) | 0.25 | pencils: Leo O'Mealia; inks: Leo O'Mealia; colors: Rick Taylor | Superman [Clark Kent] |
| 18 | Famous First Issues! [Superboy #1] | cover reprint (on interior page) | 0.25 | pencils: Wayne Boring; inks: Stan Kaye; colors: Rick Taylor | Superman (no Superboy) |
| 19 | Famous First Issues! [Superman's Pal, Jimmy Olsen #1] | cover reprint (on interior page) | 0.25 | pencils: Curt Swan; inks: Stan Kaye; colors: Rick Taylor; letters: Ira Schnapp | Jimmy Olsen; Superman [Clark Kent] |
| 20 | Famous First Issues! [Superman's Girl Friend, Lois Lane #1] | cover reprint (on interior page) | 0.25 | pencils: Curt Swan; inks: Stan Kaye; colors: Rick Taylor; letters: Ira Schnapp | Lois Lane; Superman [Clark Kent] |
| 21 | Famous First Issues! | cover reprint (on interior page) | 1 | pencils: Joe Shuster, Leo O'Mealia, Wayne Boring, Curt Swan; inks: Joe Shuster, Leo O'Mealia, Stan Kaye | Superman [Clark Kent]; Jimmy Olsen; Lois Lane |