| 0 | - | cover | 1 | pencils: Craig McCracken; inks: Craig McCracken | |
| 1 | Friend or Foe? | comic story | 8 | script: Amy Keating Rogers; pencils: Vaughn Tada; inks: Bob Harper; colors: Janice Kubo; letters: Mike Sellers | Mac; Bloo; Bob Zombie; Wilt; Frankie Foster; Coco; Eduardo |
| 2 | Movie Fight | comic story | 8 | script: Jennifer Moore; pencils: Stephanie Gladden; inks: Bob Harper; colors: Heroic Age; letters: Mike Sellers | Bloo; Eduardo; Coco; Wilt; Frankie Foster; Madam Foster |
| 3 | My Friend Frankie | comic story | 6 | script: Jennifer Moore; pencils: Stephanie Gladden; inks: Janice Kubo; colors: Heroic Age; letters: Mike Sellers | |
| 4 | Piñata Panic | comic story | 8 | script: Jennifer Moore; pencils: Stephanie Gladden; inks: Phil Moy; colors: Heroic Age; letters: Mike Sellers | Mac; Bloo; Madam Foster; Eduardo; Frankie Foster; Mr. Herriman; Wilt |
| 5 | Fair Game | comic story | 8 | script: Jennifer Moore; pencils: Stephanie Gladden; inks: Jeff Albrecht; colors: Heroic Age; letters: Mike Sellers | |
| 6 | Block Rockin' Feats | comic story | 8 | script: Jennifer Moore; pencils: Christopher Cook; inks: Jeff Albrecht; colors: Heroic Age; letters: Mike Sellers | Madam Foster; Frankie Foster; Eduardo; Wilt; Coco; Bloo |
| 7 | Tat-Bloo | comic story | 8 | script: Scott Cunningham; pencils: Stephanie Gladden; inks: Phil Moy; colors: Heroic Age; letters: Mike Sellers | Bloo; Mac; Coco; Wilt; Eduardo |
| 8 | Ill Will | comic story | 8 | script: Scott Cunningham; pencils: Robert Pope; inks: Jeff Albrecht; colors: Heroic Age; letters: Mike Sellers | Mr. Herriman; Bloo; Frankie Foster; Eduardo; Mac; Wilt; Coco; Madam Foster |
| 9 | Endanger Is My Business | comic story | 8 | script: Scott Cunningham; pencils: Robert Pope; inks: Jeff Albrecht; colors: Heroic Age; letters: Mike Sellers | Bloo; Mac; Eduardo; Wilt; Frankie Foster |
| 10 | To Love Some Bunny | comic story | 8 | script: Scott Roberts; pencils: Ricardo Garcia Fuentes; inks: Mike DeCarlo; colors: Heroic Age; letters: Travis Lanham | Powerpuff Girls [Bubbles; Blossom; Buttercup] Professor Utonium; HIM |
| 11 | The Big Green Monster | comic story | 8 | script: Robbie Busch; pencils: Ricardo Garcia Fuentes; inks: Mike DeCarlo; colors: Heroic Age; letters: Travis Lanham | Powerpuff Girls [Blossom; Buttercup; Bubbles]; Mojo Jojo; Gangreen Gang [Ace; Big Billy; Snake; Grubber; Li'l Arturo]; Professor Utonium |
| 12 | Lab Partners | comic story | 8 | script: Scott Roberts; pencils: Cindy Morrow; inks: Mike DeCarlo; colors: Heroic Age; letters: Travis Lanham | Powerpuff Girls [Buttercup; Bubbles; Blossom]; Mojo Jojo; Mayor; Professor Utonium |
| 13 | The MP Three | comic story | 10 | script: Amy Keating Rogers; pencils: Cindy Morrow; inks: Mike DeCarlo; colors: Heroic Age; letters: Ken Lopez | |
| 14 | Steal a Meal | comic story | 8 | script: Frank Strom; pencils: Christopher Cook; inks: Mike DeCarlo; colors: Heroic Age; letters: Ryan Cline | |
| 15 | Stubble and Fall | comic story | 6 | script: Frank Strom; pencils: Christopher Cook; inks: Mike DeCarlo; colors: Heroic Age; letters: John J. Hill | Blossom; Bubbles; Buttercup; Professor Utonium |
| 16 | Mayor Minor | comic story | 8 | script: Amy Keating Rogers; pencils: Christopher Cook; inks: Mike DeCarlo; colors: Heroic Age; letters: Mike Sellers | |
| 17 | Professor Mom | comic story | 4 | script: Amy Keating Rogers; pencils: Phil Moy; inks: Phil Moy; colors: Heroic Age; letters: Mike Sellers | Powerpuff Girls [Bubbles; Buttercup; Blossom]; Professor Utonium |
| 18 | Sounding Off | comic story | 6 | script: Amy Keating Rogers; pencils: Christopher Cook; inks: Mike DeCarlo; colors: Heroic Age; letters: Mike Sellers | Blossom; Buttercup; Bubbles |
| 19 | Amoeba? I Don't Even Know Ya! | comic story | 4 | script: Robbie Busch; pencils: Christopher Cook; inks: Mike DeCarlo; colors: Heroic Age; letters: Sal Cipriano | Bubbles; Blossom; Buttercup; Professor Utonium; Amoeba Boys [Bossman; Slim; Junior] |