| 0 | - | cover | 1 | pencils: Dean Haspiel; inks: Dean Haspiel; colors: Bob Fingerman | |
| 1 | - | blank page(s) | 1 | | |
| 2 | Title Pages and Publication Information | credits, title page | 4 | pencils: Ty Templeton, Mike Hawthorne, Josh Neufeld; inks: Ty Templeton, Mike Hawthorne, Josh Neufeld | |
| 3 | Part One: Chalk One Up for the Cheapskate | illustration | 1 | pencils: Philip Bond; inks: Philip Bond | |
| 4 | I'm No Help! | comic story | 8 | script: Harvey Pekar; pencils: David Lapham; inks: David Lapham; letters: Pat Brosseau | |
| 5 | Hollywood Bob's Observation | comic story | 1 | script: Harvey Pekar; pencils: Dean Haspiel; inks: Dean Haspiel; letters: Pat Brosseau | |
| 6 | Restraint | comic story | 4 | script: Harvey Pekar; pencils: Mike Hawthorne; inks: Mike Hawthorne; letters: Pat Brosseau | |
| 7 | Chicago Visit | comic story | 6 | script: Harvey Pekar; pencils: Hilary Barta; inks: Hilary Barta; letters: Pat Brosseau | |
| 8 | Grunting | comic story | 2 | script: Harvey Pekar; pencils: John Lucas; inks: John Lucas; letters: Pat Brosseau | |
| 9 | The Kirkus Reviewer | comic story | 4 | script: Harvey Pekar; pencils: Ed Piskor; inks: Ed Piskor; letters: Pat Brosseau | |
| 10 | The Casablanca | comic story | 4 | script: Harvey Pekar; pencils: Zachary Baldus; inks: Zachary Baldus; letters: Pat Brosseau | |
| 11 | Fall | comic story | 2 | script: Harvey Pekar; pencils: Chris Weston; inks: Chris Weston; letters: Pat Brosseau | |
| 12 | Part Two: Keep On Pushin' | illustration | 1 | pencils: Ty Templeton; inks: Ty Templeton | |
| 13 | You Get Old You Can Fall Apart (We're a Winner) | comic story | 8 | script: Harvey Pekar; pencils: Ty Templeton; inks: Ty Templeton; letters: Pat Brosseau | |
| 14 | Inexplicable Cat Behavior | comic story | 2 | script: Harvey Pekar; pencils: Hunt Emerson; inks: Hunt Emerson; letters: Hunt Emerson | |
| 15 | Town Meeting | comic story | 4 | script: Harvey Pekar; pencils: Gary Dumm; inks: Greg Budgett; letters: Pat Brosseau | |
| 16 | Compromise | comic story | 4 | script: Harvey Pekar; pencils: Josh Neufeld; inks: Josh Neufeld; letters: Pat Brosseau | |
| 17 | Brought Up Short | comic story | 2 | script: Harvey Pekar; pencils: Dean Haspiel; inks: Dean Haspiel; letters: Pat Brosseau | |
| 18 | Joy Moves Ahead | comic story | 4 | script: Harvey Pekar; pencils: Lora Innes; inks: José Marzan; letters: Pat Brosseau | |
| 19 | The Knowledgeable Barber | comic story | 6 | script: Harvey Pekar; pencils: David Lapham; inks: David Lapham; letters: Pat Brosseau | |
| 20 | Team Player | comic story | 1 | script: Harvey Pekar; pencils: Zachary Baldus; inks: Zachary Baldus; letters: Pat Brosseau | |
| 21 | Part Three: I'll take It, I'll Take It | illustration | 1 | pencils: Josh Neufeld; inks: Josh Neufeld | |
| 22 | How Much Pain Is Too Much? | comic story | 3 | script: Harvey Pekar; pencils: Rick Geary; inks: Rick Geary; letters: Rick Geary | |
| 23 | I've Done a lot of Stuff in My Life I'm Not Proud Of But at Least... | comic story | 2 | script: Harvey Pekar; pencils: John Cebollero; inks: John Cebollero; letters: Pat Brosseau | |
| 24 | Coventry | comic story | 7 | script: Harvey Pekar; pencils: Warren Pleece; inks: Warren Pleece; letters: Pat Brosseau | |
| 25 | Moby Dick | comic story | 2 | script: Harvey Pekar; pencils: Sean Murphy; inks: Sean Murphy; letters: Sean Murphy | |
| 26 | The Demystification of Idea Generation-Marketing Articles | comic story | 3 | script: Harvey Pekar; pencils: Chris Samnee; inks: Chris Samnee; letters: Pat Brosseau | |
| 27 | Bop Philosophy | comic story | 9 | script: Harvey Pekar; pencils: Dean Haspiel; inks: Dean Haspiel; letters: Pat Brosseau | |
| 28 | Global Warming | comic story | 3 | script: Harvey Pekar; pencils: Josh Neufeld; inks: Josh Neufeld; letters: Pat Brosseau | |
| 29 | Cousin Walter the Scientist | comic story | 2 | script: Harvey Pekar; pencils: Darwyn Cooke; inks: Darwyn Cooke; letters: Darwyn Cooke | |
| 30 | Part Four: Now I Can Breathe Again | illustration | 1 | pencils: Dean Haspiel; inks: Dean Haspiel | |
| 31 | Events That Set the Tone for the Day | comic story | 13 | script: Harvey Pekar; pencils: Darick Robertson; inks: Darick Robertson; letters: Pat Brosseau | |
| 32 | Free Association Introduction | comic story | 4 | script: Harvey Pekar; pencils: Ty Templeton; inks: Ty Templeton; letters: K.T. Smith | |
| 33 | Chapter One: Cleopatra | comic story | 5 | script: Harvey Pekar; pencils: Dean Haspiel; inks: Dean Haspiel; letters: Pat Brosseau | |
| 34 | Chapter Two: Income Tax | comic story | 2 | script: Harvey Pekar; pencils: Rick Geary; inks: Rick Geary; letters: Rick Geary | |
| 35 | Chapter Three: The Car | comic story | 5 | script: Harvey Pekar; pencils: Greg Budgett, Gary Dumm; inks: Gary Dumm; letters: Pat Brosseau | |
| 36 | Free Association Epilogue | comic story | 2 | script: Harvey Pekar; pencils: Ty Templeton; inks: Ty Templeton; letters: K.T. Smith | |
| 37 | American Splendor Season Two #1 | cover reprint (on interior page) | 1 | pencils: Philip Bond; inks: Philip Bond; colors: Philip Bond | |
| 38 | American Splendor Season Two #2 | cover reprint (on interior page) | 1 | pencils: Darick Robertson; inks: Darick Robertson; colors: Brian Buccellato | |
| 39 | American Splendor Season Two #3 | cover reprint (on interior page) | 1 | pencils: Darwyn Cooke; inks: Darwyn Cooke; colors: Darwyn Cooke | |
| 40 | American Splendor Season Two #4 | cover reprint (on interior page) | 1 | pencils: Dean Haspiel; inks: Dean Haspiel; colors: Lee Loughridge | |
| 41 | - | blank page(s) | 1 | | |
| 42 | - | promo (ad from the publisher) | 1 | pencils: Hilary Barta; inks: Hilary Barta | |