| 0 | Seed of Destruction | cover | 1 | pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart | Hellboy, Grigori Rasputin |
| 1 | - | blank page(s) | 1 | | |
| 2 | Hellboy: Seed of Destruction | credits, title page | 1 | pencils: Mike Mignola; inks: Mike Mignola | Hellboy, Grigori Rasputin |
| 3 | - | credits, title page | 1 | letters: typeset | |
| 4 | - | table of contents | 1 | letters: typeset | |
| 5 | Seed of Destruction | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart | Hellboy |
| 6 | Chapter One | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 7 | Hellboy: Seed of Destruction #1 Cover | cover reprint (on interior page) | 1 | pencils: Arthur Adams, Mike Mignola; inks: Arthur Adams, Mike Mignola | Hellboy, Monkeyman, Ann O'Brien, Axwell Tiberius |
| 8 | Seed of Destruction Chapter One | comic story | 23 | script: Mike Mignola, John Byrne; pencils: Mike Mignola; inks: Mike Mignola; colors: Mark Chiarello; letters: John Byrne, Mike Mignola | Trevor Bruttenholm, Cynthia Eden-Jones, Malcolm Frost, Ilsa Haupstein, Hellboy, Karl Ruprect Kroenen, Leopold Kurtz, Tom Manning, Grigori Rasputin, Torch of Liberty, Klaus Werner von Krupt |
| 9 | An African Myth About A Frog | text article | 1 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: Mark Chiarello | |
| 10 | Chapter Two | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 11 | Hellboy: Seed of Destruction #2 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola, Arthur Adams; inks: Arthur Adams, Mike Mignola | Hellboy, Monkeyman, Ann O'Brien, Axwell Tiberius |
| 12 | Seed of Destruction Chapter Two | comic story | 24 | script: Mike Mignola, John Byrne; pencils: Mike Mignola; inks: Mike Mignola; colors: Mark Chiarello; letters: John Byrne, Mike Mignola | Langdon Everett Caul, Hellboy, Grigori Rasputin, Abe Sapien, Liz Sherman |
| 13 | Chapter Three | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 14 | Hellboy: Seed of Destruction #3 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola, Arthur Adams; inks: Mike Mignola, Arthur Adams | Hellboy, Monkeyman, Ann O'Brien, Grigori Rasputin, Axwell Tiberius |
| 15 | Seed of Destruction Chapter Three | comic story | 24 | script: Mike Mignola, John Byrne; pencils: Mike Mignola; inks: Mike Mignola; colors: Mark Chiarello; letters: John Byrne, Mike Mignola | Trevor Bruttenholm, Langdon Everett Caul, Ilsa Haupstein, Hellboy, Karl Ruprect Kroenen, Grigori Rasputin, Abe Sapien, Liz Sherman, Klaus Werner von Krupt |
| 16 | Chapter Four | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 17 | Hellboy: Seed of Destruction #4 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola, Arthur Adams; inks: Arthur Adams, Mike Mignola | Hellboy, Monkeyman, Ann O'Brien, Grigori Rasputin, Axwell Tiberius |
| 18 | Seed of Destruction Chapter Four | comic story | 23 | script: Mike Mignola, John Byrne; pencils: Mike Mignola; inks: Mike Mignola; colors: Mark Chiarello; letters: John Byrne, Mike Mignola | Langdon Everett Caul, Ilsa Haupstein, Hellboy, Karl Ruprect Kroenen, Grigori Rasputin, Abe Sapien, Liz Sherman, Klaus Werner von Krupt |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart | Hellboy |
| 20 | The Wolves of Saint August | comic story | 41 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair; letters: Pat Brosseau, Mike Mignola; editing: Barbara Kesel, Scott Allie | Kate Corrigan, Hellboy |
| 21 | The Chained Coffin | comic story | 10 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart; letters: Pat Brosseau | Langdon Everett Caul, Hellboy, Abe Sapien |
| 22 | Wake the Devil | cover reprint (on interior page) | 1 | pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart | Vladimir Giurescu, Hellboy |
| 23 | Chapter One | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 24 | Hellboy: Wake the Devil #1 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola; inks: Mike Mignola | Vladimir Giurescu, Hellboy |
| 25 | Wake the Devil Chapter One | comic story | 22 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair, David Stewart; letters: Pat Brosseau, Mike Mignola | Langdon Everett Caul, Kate Corrigan, Vladimir Giurescu, Sir Edward Grey, Ilsa Haupstein, Hellboy, Karl Ruprect Kroenen, Leopold Kurtz, Tom Manning, Grigori Rasputin, Abe Sapien, Liz Sherman |
| 26 | Chapter Two | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 27 | Hellboy: Wake the Devil #2 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 28 | Wake the Devil Chapter Two | comic story | 22 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair, David Stewart; letters: Pat Brosseau, Mike Mignola | Vladimir Giurescu Origin, Ilsa Haupstein, Hellboy, Karl Ruprect Kroenen, Leopold Kurtz, Grigori Rasputin, Klaus Werner von Krupt |
| 29 | Chapter Three | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 30 | Hellboy: Wake the Devil #3 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 31 | Wake the Devil Chapter Three | comic story | 22 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair, David Stewart; letters: Pat Brosseau, Mike Mignola | Vladimir Giurescu, Ilsa Haupstein, Hecate, Hellboy, Karl Ruprect Kroenen, Leopold Kurtz, Grigori Rasputin Origin, Roger the Homunculus, Liz Sherman, Herman von Klempt |
| 32 | Chapter Four | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 33 | Hellboy: Wake the Devil #4 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 34 | Wake the Devil Chapter Four | comic story | 22 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair, David Stewart; letters: Pat Brosseau, Mike Mignola | Langdon Everett Caul, Kate Corrigan, Ilsa Haupstein, Hecate, Hellboy, Karl Ruprect Kroenen, Leopold Kurtz Death, Tom Manning, Grigori Rasputin, Abe Sapien, Herman von Klempt |
| 35 | Chapter Five | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 36 | Hellboy: Wake the Devil #5 Cover | cover reprint (on interior page) | 1 | pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 37 | Wake the Devil Chapter Five | comic story | 24 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair, David Stewart; letters: Pat Brosseau, Mike Mignola | Langdon Everett Caul, Kate Corrigan, Hecate, Hellboy, Karl Ruprect Kroenen, Leopold Kurtz, Grigori Rasputin, Abe Sapien, Herman von Klempt |
| 38 | Vladimir Giurescu / Nicholas Budenz | text story | 2 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart | Vladimir Giurescu |
| 39 | Epilogue | comic story | 5 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair; letters: Pat Brosseau | Grigori Rasputin |
| 40 | Almost Colossus | illustration | 1 | pencils: Mike Mignola; inks: Mike Mignola | |
| 41 | Almost Colossus | comic story | 46 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: James Sinclair, Dave Stewart; letters: Pat Brosseau | Langdon Everett Caul, Kate Corrigan, Hellboy, Tom Manning, Roger the Homunculus, Abe Sapien, Liz Sherman |
| 42 | - | illustration | 1 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 43 | - | illustration | 1 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 44 | - | illustration | 1 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 45 | - | illustration | 1 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola | Hellboy |
| 46 | Mike Mignola's Hellboy | comic story | 4 | script: Mike Mignola, John Byrne; pencils: Mike Mignola; inks: Mike Mignola; colors: Matthew Hollingsworth; letters: Mike Mignola | Hellboy, Herman von Klempt |
| 47 | Mike Mignola's Hellboy | comic story | 4 | script: Mike Mignola, John Byrne; pencils: Mike Mignola; inks: Mike Mignola; colors: Matthew Hollingsworth; letters: Mike Mignola | Hellboy |
| 48 | Hellboy Sketchbook | illustration | 18 | script: Mike Mignola; pencils: Mike Mignola; inks: Mike Mignola; colors: Mike Mignola | Hellboy |
| 49 | Also by Mike Mignola | promo (ad from the publisher) | 1 | pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart | Langdon Everett Caul, Abe Sapien |
| 50 | Hellboy by Mike Mignola | promo (ad from the publisher) | 1 | pencils: Mike Mignola; inks: Mike Mignola; colors: Dave Stewart | Hellboy |
| 51 | - | blank page(s) | 1 | | |
| 52 | - | promo (ad from the publisher) | 1 | pencils: Mike Mignola; inks: Mike Mignola | Hellboy |